Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDI1 All Species: 16.06
Human Site: S374 Identified Species: 32.12
UniProt: Q8WTU0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WTU0 NP_001001711.1 396 44124 S374 P L C S R M V S G Q D E S S D
Chimpanzee Pan troglodytes XP_001154591 392 43542 C369 P E G E L P L C S R M V S G Q
Rhesus Macaque Macaca mulatta XP_001099820 396 43990 N374 P L C S R M V N G K D E P S D
Dog Lupus familis XP_854523 472 52925 S444 P L C A K L V S S A G Q Q E S
Cat Felis silvestris
Mouse Mus musculus Q9DAF3 408 45694 S380 P L C A K L L S G T V Q E E S
Rat Rattus norvegicus A0JPP7 408 45432 S380 P L C A K L L S G A V Q E D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511851 386 43141 Y353 P E C A R L A Y G A G R D D M
Chicken Gallus gallus XP_423293 358 40255 S331 M L K R H Q C S I D L K K N V
Frog Xenopus laevis Q7ZYA7 393 43714 Y360 P E C A R L A Y G P G R E E V
Zebra Danio Brachydanio rerio Q6TH22 411 45578 Y376 P E C A R L A Y G P E G R E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573129 458 50519 G371 P V S A R L T G N S E D S M E
Honey Bee Apis mellifera XP_624431 465 51996 G358 P E W L R L S G Y S D A S N Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 96.2 69.9 N.A. 79.6 81.1 N.A. 65.4 67.6 68.6 66.4 N.A. 43.6 46.2 N.A. N.A.
Protein Similarity: 100 98.2 97.2 76.2 N.A. 87.5 88.9 N.A. 78 78 80.3 78.3 N.A. 55.6 57.6 N.A. N.A.
P-Site Identity: 100 13.3 80 33.3 N.A. 33.3 33.3 N.A. 26.6 13.3 26.6 26.6 N.A. 20 26.6 N.A. N.A.
P-Site Similarity: 100 26.6 93.3 60 N.A. 66.6 66.6 N.A. 40 26.6 40 53.3 N.A. 60 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 59 0 0 25 0 0 25 0 9 0 0 0 % A
% Cys: 0 0 67 0 0 0 9 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 9 25 9 9 17 17 % D
% Glu: 0 42 0 9 0 0 0 0 0 0 17 17 25 34 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 0 17 59 0 25 9 0 9 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 9 0 25 0 0 0 0 9 0 9 9 0 0 % K
% Leu: 0 50 0 9 9 67 25 0 0 0 9 0 0 0 0 % L
% Met: 9 0 0 0 0 17 0 0 0 0 9 0 0 9 9 % M
% Asn: 0 0 0 0 0 0 0 9 9 0 0 0 0 17 0 % N
% Pro: 92 0 0 0 0 9 0 0 0 17 0 0 9 0 0 % P
% Gln: 0 0 0 0 0 9 0 0 0 9 0 25 9 0 9 % Q
% Arg: 0 0 0 9 59 0 0 0 0 9 0 17 9 0 0 % R
% Ser: 0 0 9 17 0 0 9 42 17 17 0 0 34 17 25 % S
% Thr: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % T
% Val: 0 9 0 0 0 0 25 0 0 0 17 9 0 0 17 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 25 9 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _