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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCARB1 All Species: 4.55
Human Site: S466 Identified Species: 12.5
UniProt: Q8WTV0 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WTV0 NP_005496.4 552 60878 S466 P V I C Q I R S Q V G A G Q R
Chimpanzee Pan troglodytes XP_509475 657 72616 S570 P L L W F A E S G A M E G E T
Rhesus Macaque Macaca mulatta XP_001101812 446 49068 A361 L W F A E S G A M E G E T L H
Dog Lupus familis XP_543366 569 63984 S479 P L V W F E E S G A M E G K P
Cat Felis silvestris
Mouse Mus musculus Q61009 509 56735 G424 E Q S G A M G G K P L S T F Y
Rat Rattus norvegicus P97943 509 56939 G424 E Q S G M M G G K T L N T F Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508198 525 59737 G440 G E S G M M G G K T L K T F Y
Chicken Gallus gallus XP_415106 503 55900 Y418 L W F A E S G Y I D G S V L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27367 457 52316 M372 Y V D A V S G M K P E K E K H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.3 71.7 68.7 N.A. 68.4 67.7 N.A. 62.8 55.2 N.A. N.A. N.A. 24.8 N.A. N.A. N.A.
Protein Similarity: 100 73.9 75 79 N.A. 79.1 79.7 N.A. 74 73.5 N.A. N.A. N.A. 41.4 N.A. N.A. N.A.
P-Site Identity: 100 20 6.6 20 N.A. 0 0 N.A. 0 6.6 N.A. N.A. N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 40 20 40 N.A. 20 13.3 N.A. 13.3 20 N.A. N.A. N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 34 12 12 0 12 0 23 0 12 0 0 0 % A
% Cys: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 0 0 0 0 0 12 0 0 0 0 0 % D
% Glu: 23 12 0 0 23 12 23 0 0 12 12 34 12 12 0 % E
% Phe: 0 0 23 0 23 0 0 0 0 0 0 0 0 34 0 % F
% Gly: 12 0 0 34 0 0 67 34 23 0 34 0 34 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % H
% Ile: 0 0 12 0 0 12 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 45 0 0 23 0 23 0 % K
% Leu: 23 23 12 0 0 0 0 0 0 0 34 0 0 23 0 % L
% Met: 0 0 0 0 23 34 0 12 12 0 23 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % N
% Pro: 34 0 0 0 0 0 0 0 0 23 0 0 0 0 12 % P
% Gln: 0 23 0 0 12 0 0 0 12 0 0 0 0 12 0 % Q
% Arg: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 12 % R
% Ser: 0 0 34 0 0 34 0 34 0 0 0 23 0 0 12 % S
% Thr: 0 0 0 0 0 0 0 0 0 23 0 0 45 0 12 % T
% Val: 0 23 12 0 12 0 0 0 0 12 0 0 12 0 0 % V
% Trp: 0 23 0 23 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 0 0 0 0 0 0 12 0 0 0 0 0 0 34 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _