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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCARB1
All Species:
0.61
Human Site:
T497
Identified Species:
1.67
UniProt:
Q8WTV0
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTV0
NP_005496.4
552
60878
T497
S
D
R
T
L
W
P
T
A
A
W
S
P
P
P
Chimpanzee
Pan troglodytes
XP_509475
657
72616
A601
Y
A
Q
Y
V
L
L
A
L
G
C
V
L
L
L
Rhesus Macaque
Macaca mulatta
XP_001101812
446
49068
G392
Q
Y
V
L
L
A
L
G
C
V
L
L
L
V
P
Dog
Lupus familis
XP_543366
569
63984
A510
Y
A
Q
Y
V
L
L
A
L
G
C
I
L
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61009
509
56735
L455
L
L
G
L
G
G
L
L
L
L
V
P
I
I
C
Rat
Rattus norvegicus
P97943
509
56939
L455
L
L
G
L
G
G
L
L
L
L
V
P
I
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508198
525
59737
L471
F
I
G
L
G
G
V
L
L
I
I
S
F
I
L
Chicken
Gallus gallus
XP_415106
503
55900
S449
Q
Y
I
F
L
G
L
S
V
P
L
I
I
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27367
457
52316
M403
H
G
R
I
Q
I
N
M
M
I
E
P
D
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.3
71.7
68.7
N.A.
68.4
67.7
N.A.
62.8
55.2
N.A.
N.A.
N.A.
24.8
N.A.
N.A.
N.A.
Protein Similarity:
100
73.9
75
79
N.A.
79.1
79.7
N.A.
74
73.5
N.A.
N.A.
N.A.
41.4
N.A.
N.A.
N.A.
P-Site Identity:
100
0
13.3
0
N.A.
0
0
N.A.
6.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
13.3
N.A.
0
0
N.A.
6.6
13.3
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
0
0
12
0
23
12
12
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
23
0
0
0
12
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
0
0
12
12
12
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% E
% Phe:
12
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
12
34
0
34
45
0
12
0
23
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
12
12
0
12
0
0
0
23
12
23
34
34
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
23
23
0
45
34
23
67
34
56
23
23
12
34
23
34
% L
% Met:
0
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
12
0
34
12
12
23
% P
% Gln:
23
0
23
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
0
0
0
12
0
0
0
23
0
12
0
% S
% Thr:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
23
0
12
0
12
12
23
12
0
12
0
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
12
0
0
0
0
% W
% Tyr:
23
23
0
23
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _