KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THAP3
All Species:
10.3
Human Site:
S106
Identified Species:
22.67
UniProt:
Q8WTV1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTV1
NP_612359.2
239
27059
S106
S
E
R
G
N
A
S
S
S
Q
K
E
K
V
L
Chimpanzee
Pan troglodytes
XP_514343
239
27036
S106
N
E
R
G
N
A
S
S
S
Q
K
E
K
V
L
Rhesus Macaque
Macaca mulatta
XP_001094480
239
26983
S106
S
E
R
G
N
A
S
S
S
Q
K
E
K
G
L
Dog
Lupus familis
XP_849390
225
25199
S106
G
G
D
T
N
V
D
S
H
K
E
V
S
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ25
218
24609
R103
A
G
G
D
S
S
G
R
N
M
D
T
T
L
E
Rat
Rattus norvegicus
Q5U208
210
24670
P95
E
K
K
E
E
L
E
P
Q
E
Q
L
P
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520507
127
14217
W12
R
P
E
L
L
K
E
W
V
L
N
I
G
R
S
Chicken
Gallus gallus
Q5ZHN5
413
46679
E109
E
I
R
R
E
D
Q
E
E
T
T
K
N
V
E
Frog
Xenopus laevis
Q6DDT6
225
26128
P105
Q
L
P
A
E
L
E
P
V
P
A
V
P
E
V
Zebra Danio
Brachydanio rerio
Q1JPT7
225
25689
P105
N
V
C
A
T
A
E
P
L
S
E
C
F
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782462
403
45198
K106
Q
K
K
E
I
V
I
K
F
P
P
K
K
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.5
70.2
N.A.
70.7
27.6
N.A.
35.9
23.4
24.6
24.2
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
99.5
96.6
75.3
N.A.
76.9
45.6
N.A.
42.2
38.2
43.5
40.5
N.A.
N.A.
N.A.
N.A.
37.2
P-Site Identity:
100
93.3
93.3
20
N.A.
0
0
N.A.
0
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
33.3
N.A.
33.3
26.6
N.A.
0
20
6.6
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
19
0
37
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
10
0
10
10
0
0
0
10
0
0
0
0
% D
% Glu:
19
28
10
19
28
0
37
10
10
10
19
28
0
10
28
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% F
% Gly:
10
19
10
28
0
0
10
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
10
0
0
0
0
10
0
0
0
% I
% Lys:
0
19
19
0
0
10
0
10
0
10
28
19
37
0
0
% K
% Leu:
0
10
0
10
10
19
0
0
10
10
0
10
0
19
28
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
19
0
0
0
37
0
0
0
10
0
10
0
10
0
0
% N
% Pro:
0
10
10
0
0
0
0
28
0
19
10
0
19
10
10
% P
% Gln:
19
0
0
0
0
0
10
0
10
28
10
0
0
0
0
% Q
% Arg:
10
0
37
10
0
0
0
10
0
0
0
0
0
10
10
% R
% Ser:
19
0
0
0
10
10
28
37
28
10
0
0
10
10
10
% S
% Thr:
0
0
0
10
10
0
0
0
0
10
10
10
10
0
0
% T
% Val:
0
10
0
0
0
19
0
0
19
0
0
19
0
37
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _