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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG1
All Species:
28.18
Human Site:
S222
Identified Species:
62
UniProt:
Q8WTW3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTW3
NP_061184.1
980
108978
S222
I
M
L
L
E
E
S
S
P
R
Q
A
L
T
D
Chimpanzee
Pan troglodytes
XP_001167551
980
109018
S222
I
M
L
L
E
E
S
S
P
R
Q
A
L
T
D
Rhesus Macaque
Macaca mulatta
XP_001086027
980
108912
S222
I
M
L
L
E
E
S
S
P
R
Q
A
L
T
D
Dog
Lupus familis
XP_540401
1082
120421
S323
I
M
L
L
E
E
S
S
P
R
Q
A
L
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z160
980
109032
S221
I
M
L
L
E
E
S
S
P
R
Q
A
L
T
D
Rat
Rattus norvegicus
NP_001100532
980
108683
S221
I
M
L
L
E
E
S
S
P
R
Q
A
L
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025878
954
105411
S203
I
M
L
L
E
D
S
S
P
R
Q
A
L
A
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002661206
695
77047
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGC3
886
99698
S164
G
L
Q
L
D
G
Q
S
A
L
M
Q
K
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795647
920
103020
M198
K
N
A
T
A
S
D
M
V
I
T
K
A
L
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_974788
1034
114945
D235
V
A
V
V
D
E
L
D
P
E
Q
V
L
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
80.7
N.A.
85.5
85.9
N.A.
N.A.
65.7
N.A.
42.5
N.A.
25
N.A.
N.A.
36.7
Protein Similarity:
100
99.9
99
85.2
N.A.
92.4
91.7
N.A.
N.A.
77.7
N.A.
55
N.A.
43.5
N.A.
N.A.
56.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
N.A.
0
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
0
N.A.
26.6
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
0
0
10
0
0
64
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
19
10
10
10
0
0
0
0
0
0
64
% D
% Glu:
0
0
0
0
64
64
0
0
0
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
64
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% K
% Leu:
0
10
64
73
0
0
10
0
0
10
0
0
73
19
10
% L
% Met:
0
64
0
0
0
0
0
10
0
0
10
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
10
% P
% Gln:
0
0
10
0
0
0
10
0
0
0
73
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
64
73
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
10
0
0
55
0
% T
% Val:
10
0
10
10
0
0
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _