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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COG1 All Species: 26.97
Human Site: S917 Identified Species: 59.33
UniProt: Q8WTW3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WTW3 NP_061184.1 980 108978 S917 R F G L L P L S M T S T R K A
Chimpanzee Pan troglodytes XP_001167551 980 109018 S917 R F G L L P L S M T S T R K A
Rhesus Macaque Macaca mulatta XP_001086027 980 108912 S917 R F G L L P L S M T S T R K A
Dog Lupus familis XP_540401 1082 120421 S1018 R F G L L P L S M T S T R K A
Cat Felis silvestris
Mouse Mus musculus Q9Z160 980 109032 S915 R F G L L P L S M T S T R K A
Rat Rattus norvegicus NP_001100532 980 108683 S915 R F G L L P L S M T S T R K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025878 954 105411 S890 R F G L L P L S M S S S R K T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002661206 695 77047 V633 G K Q G G V D V V S R G T P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGC3 886 99698 V824 W F P L L P I V M P Q A A G R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795647 920 103020 V858 L P L T A K Q V R F S L L P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_974788 1034 114945 A963 F K Y L P I S A P A L S S R S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.4 80.7 N.A. 85.5 85.9 N.A. N.A. 65.7 N.A. 42.5 N.A. 25 N.A. N.A. 36.7
Protein Similarity: 100 99.9 99 85.2 N.A. 92.4 91.7 N.A. N.A. 77.7 N.A. 55 N.A. 43.5 N.A. N.A. 56.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 80 N.A. 0 N.A. 33.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 N.A. 13.3 N.A. 40 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 22.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 41.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 10 0 10 0 10 10 0 55 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 73 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 10 0 64 10 10 0 0 0 0 0 0 10 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 19 0 0 0 10 0 0 0 0 0 0 0 64 0 % K
% Leu: 10 0 10 82 73 0 64 0 0 0 10 10 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 73 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 10 0 10 73 0 0 10 10 0 0 0 19 0 % P
% Gln: 0 0 10 0 0 0 10 0 0 0 10 0 0 0 0 % Q
% Arg: 64 0 0 0 0 0 0 0 10 0 10 0 64 10 19 % R
% Ser: 0 0 0 0 0 0 10 64 0 19 73 19 10 0 10 % S
% Thr: 0 0 0 10 0 0 0 0 0 55 0 55 10 0 10 % T
% Val: 0 0 0 0 0 10 0 28 10 0 0 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _