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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUSC4
All Species:
22.73
Human Site:
S266
Identified Species:
55.56
UniProt:
Q8WTW4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTW4
NP_006536.3
380
43658
S266
S
L
Q
E
A
C
L
S
Y
V
T
K
Q
G
H
Chimpanzee
Pan troglodytes
XP_001169182
380
43610
S266
S
L
Q
E
A
C
L
S
Y
V
T
K
Q
G
H
Rhesus Macaque
Macaca mulatta
XP_001099730
380
43594
S266
S
L
Q
E
A
C
L
S
Y
V
T
K
Q
G
H
Dog
Lupus familis
XP_533817
380
43615
S266
S
L
Q
E
A
C
L
S
Y
V
T
K
Q
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUE4
380
43626
S266
S
L
Q
E
A
C
L
S
Y
V
T
K
Q
G
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518382
389
44819
A266
I
L
Q
E
E
C
L
A
Y
V
T
K
Q
G
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080102
378
43522
N265
A
L
Q
E
E
C
L
N
Y
V
S
K
P
G
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392834
395
45638
T275
K
L
Q
E
R
C
I
T
Y
T
S
K
F
P
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185334
392
45030
E269
Q
L
Q
R
E
C
I
E
Y
V
T
L
P
G
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39923
615
69840
S336
L
M
A
S
D
C
Q
S
Y
V
T
F
P
E
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.9
98.4
N.A.
98.4
N.A.
N.A.
86.8
N.A.
81.3
N.A.
N.A.
N.A.
48
N.A.
53.3
Protein Similarity:
100
99.7
99.4
99.4
N.A.
99.4
N.A.
N.A.
91.2
N.A.
90
N.A.
N.A.
N.A.
69.6
N.A.
70.1
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
80
N.A.
60
N.A.
N.A.
N.A.
40
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
N.A.
80
N.A.
N.A.
N.A.
60
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
50
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
80
30
0
0
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% H
% Ile:
10
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% K
% Leu:
10
90
0
0
0
0
70
0
0
0
0
10
0
0
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
30
10
0
% P
% Gln:
10
0
90
0
0
0
10
0
0
0
0
0
60
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
50
0
0
10
0
0
0
60
0
0
20
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
10
80
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
90
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _