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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUSC4
All Species:
32.73
Human Site:
S277
Identified Species:
80
UniProt:
Q8WTW4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTW4
NP_006536.3
380
43658
S277
K
Q
G
H
K
R
A
S
L
R
D
V
F
Q
L
Chimpanzee
Pan troglodytes
XP_001169182
380
43610
S277
K
Q
G
H
K
R
A
S
L
R
D
V
F
Q
L
Rhesus Macaque
Macaca mulatta
XP_001099730
380
43594
S277
K
Q
G
H
K
R
A
S
L
R
D
V
F
Q
L
Dog
Lupus familis
XP_533817
380
43615
S277
K
Q
G
H
K
R
A
S
L
R
D
V
F
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUE4
380
43626
S277
K
Q
G
H
K
R
A
S
L
R
D
V
F
Q
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518382
389
44819
S277
K
Q
G
H
K
R
A
S
L
R
D
V
F
Q
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080102
378
43522
S276
K
P
G
L
K
R
P
S
L
R
D
V
F
Q
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392834
395
45638
Y286
K
F
P
R
Q
P
A
Y
L
R
D
I
Y
R
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185334
392
45030
T280
L
P
G
H
N
P
P
T
L
R
S
V
M
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39923
615
69840
S347
F
P
E
V
S
K
I
S
N
L
P
L
N
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.9
98.4
N.A.
98.4
N.A.
N.A.
86.8
N.A.
81.3
N.A.
N.A.
N.A.
48
N.A.
53.3
Protein Similarity:
100
99.7
99.4
99.4
N.A.
99.4
N.A.
N.A.
91.2
N.A.
90
N.A.
N.A.
N.A.
69.6
N.A.
70.1
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
80
N.A.
N.A.
N.A.
33.3
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
80
N.A.
N.A.
N.A.
66.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
10
0
0
0
0
0
0
0
0
0
0
70
0
0
% F
% Gly:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% I
% Lys:
80
0
0
0
70
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
10
0
0
10
0
0
0
0
90
10
0
10
0
10
80
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% M
% Asn:
0
0
0
0
10
0
0
0
10
0
0
0
10
0
0
% N
% Pro:
0
30
10
0
0
20
20
0
0
0
10
0
0
0
0
% P
% Gln:
0
60
0
0
10
0
0
0
0
0
0
0
0
70
0
% Q
% Arg:
0
0
0
10
0
70
0
0
0
90
0
0
0
10
0
% R
% Ser:
0
0
0
0
10
0
0
80
0
0
10
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
80
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _