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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUSC4
All Species:
24.24
Human Site:
Y329
Identified Species:
59.26
UniProt:
Q8WTW4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WTW4
NP_006536.3
380
43658
Y329
L
I
R
R
L
Q
K
Y
P
V
R
V
T
R
E
Chimpanzee
Pan troglodytes
XP_001169182
380
43610
Y329
L
I
R
R
L
Q
K
Y
P
V
R
V
T
R
E
Rhesus Macaque
Macaca mulatta
XP_001099730
380
43594
Y329
L
I
R
R
L
Q
K
Y
P
V
R
V
S
R
E
Dog
Lupus familis
XP_533817
380
43615
Y329
L
I
R
R
L
Q
K
Y
P
V
R
V
S
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUE4
380
43626
Y329
L
I
R
R
L
Q
K
Y
P
V
R
V
S
R
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518382
389
44819
Y329
L
M
R
R
L
Q
K
Y
P
V
K
I
M
Q
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080102
378
43522
K327
K
L
I
R
R
L
H
K
Y
P
V
K
V
S
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392834
395
45638
G344
K
Y
P
I
Y
L
S
G
S
P
C
N
E
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185334
392
45030
G341
V
K
L
Q
T
A
D
G
Q
H
N
G
Q
H
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39923
615
69840
T564
S
L
A
T
G
K
S
T
M
P
K
L
S
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.9
98.4
N.A.
98.4
N.A.
N.A.
86.8
N.A.
81.3
N.A.
N.A.
N.A.
48
N.A.
53.3
Protein Similarity:
100
99.7
99.4
99.4
N.A.
99.4
N.A.
N.A.
91.2
N.A.
90
N.A.
N.A.
N.A.
69.6
N.A.
70.1
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
N.A.
N.A.
66.6
N.A.
6.6
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
93.3
N.A.
13.3
N.A.
N.A.
N.A.
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
70
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
20
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
10
0
0
0
10
0
% H
% Ile:
0
50
10
10
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
20
10
0
0
0
10
60
10
0
0
20
10
0
0
0
% K
% Leu:
60
20
10
0
60
20
0
0
0
0
0
10
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
10
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
10
% N
% Pro:
0
0
10
0
0
0
0
0
60
30
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
60
0
0
10
0
0
0
10
10
0
% Q
% Arg:
0
0
60
70
10
0
0
0
0
0
50
0
0
50
10
% R
% Ser:
10
0
0
0
0
0
20
0
10
0
0
0
40
10
0
% S
% Thr:
0
0
0
10
10
0
0
10
0
0
0
0
20
0
10
% T
% Val:
10
0
0
0
0
0
0
0
0
60
10
50
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
60
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _