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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYROXD1
All Species:
22.42
Human Site:
S226
Identified Species:
41.11
UniProt:
Q8WU10
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU10
NP_079130.2
500
55793
S226
K
K
E
A
R
S
K
S
K
A
D
N
V
G
S
Chimpanzee
Pan troglodytes
XP_520786
500
55723
S226
K
K
E
A
R
S
K
S
K
A
D
N
V
G
S
Rhesus Macaque
Macaca mulatta
XP_001098386
500
55757
S226
K
K
E
A
R
S
K
S
K
A
D
N
V
G
S
Dog
Lupus familis
XP_534871
564
62639
S289
K
K
E
A
Q
T
K
S
G
A
G
N
L
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3TMV7
498
55573
S223
K
K
E
T
R
T
K
S
K
A
D
Y
V
G
S
Rat
Rattus norvegicus
Q68FS6
498
55471
S223
K
K
E
T
S
T
K
S
K
A
D
Y
V
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507787
271
29578
Chicken
Gallus gallus
XP_416422
500
55202
A226
K
K
E
R
P
T
A
A
A
S
D
K
L
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PBT5
490
54238
T216
C
K
R
A
R
Y
T
T
D
S
S
A
A
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610023
472
52333
K205
S
S
P
V
V
A
I
K
R
M
R
Y
S
E
V
Honey Bee
Apis mellifera
XP_624926
477
53873
K210
A
N
K
S
S
L
T
K
R
M
R
Y
T
V
S
Nematode Worm
Caenorhab. elegans
NP_495754
451
50706
Q184
F
F
P
E
D
I
E
Q
F
I
E
K
R
L
L
Sea Urchin
Strong. purpuratus
XP_782117
495
54197
K222
S
S
E
D
D
T
G
K
E
A
G
V
M
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.1
74.6
N.A.
85
85.1
N.A.
40.2
77
N.A.
64
N.A.
46.4
50
32.7
57.4
Protein Similarity:
100
99.5
98
81.2
N.A.
90.8
91.5
N.A.
44.4
86.8
N.A.
80.4
N.A.
62.2
66
54
72.2
P-Site Identity:
100
100
100
66.6
N.A.
80
73.3
N.A.
0
40
N.A.
26.6
N.A.
0
6.6
0
26.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
80
N.A.
0
66.6
N.A.
40
N.A.
13.3
26.6
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
39
0
8
8
8
8
54
0
8
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
16
0
0
0
8
0
47
0
0
0
0
% D
% Glu:
0
0
62
8
0
0
8
0
8
0
8
0
0
8
0
% E
% Phe:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
8
0
16
0
0
70
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
8
0
0
8
0
0
0
0
0
% I
% Lys:
54
62
8
0
0
0
47
24
39
0
0
16
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
0
0
16
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
16
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
31
0
0
0
% N
% Pro:
0
0
16
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
8
39
0
0
0
16
0
16
0
8
0
0
% R
% Ser:
16
16
0
8
16
24
0
47
0
16
8
0
8
0
70
% S
% Thr:
0
0
0
16
0
39
16
8
0
0
0
0
8
0
0
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
8
39
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
31
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _