KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYROXD1
All Species:
22.12
Human Site:
Y267
Identified Species:
40.56
UniProt:
Q8WU10
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU10
NP_079130.2
500
55793
Y267
M
C
E
V
K
K
I
Y
L
Q
D
E
F
R
I
Chimpanzee
Pan troglodytes
XP_520786
500
55723
Y267
M
C
E
V
K
K
I
Y
L
Q
D
E
F
R
I
Rhesus Macaque
Macaca mulatta
XP_001098386
500
55757
Y267
M
C
E
V
K
K
I
Y
L
Q
D
E
F
R
I
Dog
Lupus familis
XP_534871
564
62639
Y330
M
C
E
V
K
K
I
Y
L
Q
E
E
F
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3TMV7
498
55573
Y264
R
C
E
V
K
K
I
Y
L
E
E
E
F
K
I
Rat
Rattus norvegicus
Q68FS6
498
55471
Y264
K
C
E
V
K
K
I
Y
L
Q
E
E
F
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507787
271
29578
Q45
C
A
E
Q
L
A
V
Q
F
P
S
E
D
I
L
Chicken
Gallus gallus
XP_416422
500
55202
H267
L
C
E
V
K
K
I
H
S
Q
Q
E
F
I
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PBT5
490
54238
E257
S
V
R
G
V
H
I
E
Y
E
C
E
V
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610023
472
52333
L246
R
E
G
E
E
N
R
L
P
K
I
Y
Y
K
S
Honey Bee
Apis mellifera
XP_624926
477
53873
E251
K
S
A
K
V
Q
I
E
Y
E
C
E
I
I
K
Nematode Worm
Caenorhab. elegans
NP_495754
451
50706
G225
E
N
M
N
N
P
S
G
P
A
L
G
P
D
W
Sea Urchin
Strong. purpuratus
XP_782117
495
54197
L263
K
C
E
I
Q
E
L
L
T
P
E
E
A
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.1
74.6
N.A.
85
85.1
N.A.
40.2
77
N.A.
64
N.A.
46.4
50
32.7
57.4
Protein Similarity:
100
99.5
98
81.2
N.A.
90.8
91.5
N.A.
44.4
86.8
N.A.
80.4
N.A.
62.2
66
54
72.2
P-Site Identity:
100
100
100
93.3
N.A.
73.3
80
N.A.
13.3
60
N.A.
13.3
N.A.
0
13.3
0
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
73.3
N.A.
20
N.A.
26.6
26.6
0
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
0
0
0
8
0
0
8
0
0
% A
% Cys:
8
62
0
0
0
0
0
0
0
0
16
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
24
0
8
8
0
% D
% Glu:
8
8
70
8
8
8
0
16
0
24
31
85
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
54
0
0
% F
% Gly:
0
0
8
8
0
0
0
8
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
70
0
0
0
8
0
8
24
47
% I
% Lys:
24
0
0
8
54
54
0
0
0
8
0
0
0
31
16
% K
% Leu:
8
0
0
0
8
0
8
16
47
0
8
0
0
0
8
% L
% Met:
31
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
8
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
16
16
0
0
8
0
0
% P
% Gln:
0
0
0
8
8
8
0
8
0
47
8
0
0
0
16
% Q
% Arg:
16
0
8
0
0
0
8
0
0
0
0
0
0
31
0
% R
% Ser:
8
8
0
0
0
0
8
0
8
0
8
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
8
0
54
16
0
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
47
16
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _