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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF139
All Species:
21.82
Human Site:
Y41
Identified Species:
40
UniProt:
Q8WU17
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU17
NP_009149.2
664
75994
Y41
I
D
A
I
F
N
S
Y
P
D
S
S
Q
S
R
Chimpanzee
Pan troglodytes
XP_519946
664
75923
Y41
I
D
A
I
F
N
S
Y
P
D
S
S
Q
S
R
Rhesus Macaque
Macaca mulatta
XP_001102164
664
75899
Y41
I
D
A
I
F
N
S
Y
P
D
S
S
Q
S
R
Dog
Lupus familis
XP_851772
664
75982
Y41
I
D
A
I
F
N
S
Y
Y
D
S
S
Q
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMV1
668
76166
Y41
I
D
A
I
F
N
S
Y
Y
D
S
S
Q
S
R
Rat
Rattus norvegicus
NP_001121017
656
75015
Y29
I
D
A
I
F
N
S
Y
Y
D
S
S
Q
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511517
606
68199
Chicken
Gallus gallus
NP_001026126
662
74815
A41
I
D
A
I
F
N
S
A
P
L
P
G
G
S
V
Frog
Xenopus laevis
Q5BIY5
695
78476
D30
L
D
V
L
Y
R
W
D
V
S
S
F
F
Q
Q
Zebra Danio
Brachydanio rerio
Q7ZWF4
685
77631
D30
L
E
V
L
Y
R
W
D
V
S
S
F
F
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRW1
809
89216
D30
I
D
E
I
L
K
M
D
M
G
M
Q
S
W
L
Honey Bee
Apis mellifera
XP_392068
661
75864
G32
I
D
E
L
L
R
I
G
L
G
L
S
N
D
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795746
565
64288
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.4
96.3
N.A.
92.9
92.3
N.A.
76
78.7
26
25.2
N.A.
31.6
37.7
N.A.
35
Protein Similarity:
100
99.5
98.8
98
N.A.
95.5
94.7
N.A.
83.4
87.8
46.4
46.1
N.A.
48.4
57.6
N.A.
51.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
60
13.3
6.6
N.A.
20
20
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
60
40
40
N.A.
20
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
54
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
77
0
0
0
0
0
24
0
47
0
0
0
8
0
% D
% Glu:
0
8
16
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
54
0
0
0
0
0
0
16
16
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
16
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
70
0
0
62
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% K
% Leu:
16
0
0
24
16
0
0
0
8
8
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
54
0
0
0
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
31
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
47
16
8
% Q
% Arg:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
47
% R
% Ser:
0
0
0
0
0
0
54
0
0
16
62
54
8
54
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
16
0
0
0
0
0
16
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
16
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
16
0
0
47
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _