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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF139
All Species:
33.03
Human Site:
Y462
Identified Species:
60.56
UniProt:
Q8WU17
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU17
NP_009149.2
664
75994
Y462
E
K
L
D
D
Y
V
Y
Y
V
R
S
T
G
S
Chimpanzee
Pan troglodytes
XP_519946
664
75923
Y462
E
K
L
D
D
Y
V
Y
Y
V
R
S
T
G
S
Rhesus Macaque
Macaca mulatta
XP_001102164
664
75899
Y462
E
K
L
D
D
Y
V
Y
Y
V
R
S
T
G
S
Dog
Lupus familis
XP_851772
664
75982
Y462
E
K
L
D
D
Y
V
Y
Y
V
R
S
T
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMV1
668
76166
Y462
E
K
L
D
D
Y
V
Y
F
V
R
S
T
G
N
Rat
Rattus norvegicus
NP_001121017
656
75015
Y450
E
K
L
D
D
Y
V
Y
F
V
R
S
T
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511517
606
68199
Y408
L
W
E
K
L
D
D
Y
V
Y
Y
V
R
S
T
Chicken
Gallus gallus
NP_001026126
662
74815
D462
V
L
W
E
K
L
D
D
Y
V
Y
Y
V
R
S
Frog
Xenopus laevis
Q5BIY5
695
78476
Y452
E
N
V
D
D
A
I
Y
Y
V
N
G
T
Y
R
Zebra Danio
Brachydanio rerio
Q7ZWF4
685
77631
Y452
E
N
M
D
E
V
I
Y
Y
V
N
G
T
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRW1
809
89216
Y531
E
K
L
D
D
Y
L
Y
Y
V
R
A
F
G
N
Honey Bee
Apis mellifera
XP_392068
661
75864
N455
L
W
S
H
Y
T
V
N
T
W
L
L
A
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795746
565
64288
G367
L
W
T
T
N
H
I
G
T
W
M
L
A
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.4
96.3
N.A.
92.9
92.3
N.A.
76
78.7
26
25.2
N.A.
31.6
37.7
N.A.
35
Protein Similarity:
100
99.5
98.8
98
N.A.
95.5
94.7
N.A.
83.4
87.8
46.4
46.1
N.A.
48.4
57.6
N.A.
51.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
6.6
20
46.6
40
N.A.
73.3
13.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
26.6
60
60
N.A.
93.3
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
8
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
70
62
8
16
8
0
0
0
0
0
0
0
% D
% Glu:
70
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
16
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
16
0
54
0
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% I
% Lys:
0
54
0
8
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
24
8
54
0
8
8
8
0
0
0
8
16
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
16
0
0
8
0
0
8
0
0
16
0
0
0
31
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
54
0
8
8
16
% R
% Ser:
0
0
8
0
0
0
0
0
0
0
0
47
0
8
39
% S
% Thr:
0
0
8
8
0
8
0
0
16
0
0
0
62
0
16
% T
% Val:
8
0
8
0
0
8
54
0
8
77
0
8
8
8
0
% V
% Trp:
0
24
8
0
0
0
0
0
0
16
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
54
0
77
62
8
16
8
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _