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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRS2 All Species: 17.27
Human Site: S211 Identified Species: 34.55
UniProt: Q8WU20 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WU20 NP_001036020.1 508 57029 S211 E E R K N R T S V H V P L E A
Chimpanzee Pan troglodytes XP_522464 508 57026 S211 E E R K N R T S V H V P L E A
Rhesus Macaque Macaca mulatta XP_001084538 492 54416 H207 D D H R R G R H C L Q P L P E
Dog Lupus familis XP_850500 508 57011 S211 E E R K N R T S V H V P L E A
Cat Felis silvestris
Mouse Mus musculus Q8C180 508 56775 S211 E E R K N R A S V H V P P E A
Rat Rattus norvegicus Q52RG8 492 54329 P198 S H T Y V N T P T G E E D R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518131 552 59439 G240 E G A K S H L G V P V G T T L
Chicken Gallus gallus XP_416087 508 57269 S211 E E R K N R S S V H A P L E S
Frog Xenopus laevis P07222 299 33514 P15 D N I A P L R P Q N F L F G C
Zebra Danio Brachydanio rerio XP_001923962 485 53928 R198 T T G L Q E E R R C R S T G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122793 483 53108 P195 P V L P P P P P P P P F P Q P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781457 717 77816 R266 D P A L N Y A R L K L P S D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 48.2 99.2 N.A. 95.8 49.6 N.A. 42.5 92.7 20.8 65.3 N.A. N.A. 20.6 N.A. 25.8
Protein Similarity: 100 99.8 65.7 100 N.A. 98 64.9 N.A. 57.2 96.4 32.2 75 N.A. N.A. 37.2 N.A. 40.1
P-Site Identity: 100 100 13.3 100 N.A. 86.6 6.6 N.A. 26.6 80 0 0 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 33.3 100 N.A. 86.6 6.6 N.A. 33.3 93.3 13.3 0 N.A. N.A. 6.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 9 0 0 17 0 0 0 9 0 0 0 34 % A
% Cys: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 9 % C
% Asp: 25 9 0 0 0 0 0 0 0 0 0 0 9 9 0 % D
% Glu: 50 42 0 0 0 9 9 0 0 0 9 9 0 42 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 9 9 0 0 % F
% Gly: 0 9 9 0 0 9 0 9 0 9 0 9 0 17 0 % G
% His: 0 9 9 0 0 9 0 9 0 42 0 0 0 0 9 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 50 0 0 0 0 0 9 0 0 0 0 0 % K
% Leu: 0 0 9 17 0 9 9 0 9 9 9 9 42 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 50 9 0 0 0 9 0 0 0 0 0 % N
% Pro: 9 9 0 9 17 9 9 25 9 17 9 59 17 9 9 % P
% Gln: 0 0 0 0 9 0 0 0 9 0 9 0 0 9 0 % Q
% Arg: 0 0 42 9 9 42 17 17 9 0 9 0 0 9 9 % R
% Ser: 9 0 0 0 9 0 9 42 0 0 0 9 9 0 9 % S
% Thr: 9 9 9 0 0 0 34 0 9 0 0 0 17 9 0 % T
% Val: 0 9 0 0 9 0 0 0 50 0 42 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _