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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRS2
All Species:
19.7
Human Site:
S318
Identified Species:
39.39
UniProt:
Q8WU20
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU20
NP_001036020.1
508
57029
S318
G
L
S
I
P
S
A
S
G
V
R
R
G
R
L
Chimpanzee
Pan troglodytes
XP_522464
508
57026
S318
G
L
S
I
P
S
A
S
G
V
R
R
G
R
L
Rhesus Macaque
Macaca mulatta
XP_001084538
492
54416
L302
R
R
G
A
G
W
R
L
N
P
E
E
P
G
W
Dog
Lupus familis
XP_850500
508
57011
S318
G
L
S
I
P
S
A
S
G
V
R
R
G
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C180
508
56775
S318
G
L
S
I
P
S
A
S
G
V
R
R
G
R
L
Rat
Rattus norvegicus
Q52RG8
492
54329
L302
Q
Q
G
A
G
W
R
L
S
P
E
E
R
G
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518131
552
59439
Y362
R
R
A
P
L
L
H
Y
E
N
L
P
A
L
P
Chicken
Gallus gallus
XP_416087
508
57269
S318
R
L
S
I
P
S
A
S
G
V
R
R
G
R
L
Frog
Xenopus laevis
P07222
299
33514
G109
L
R
L
K
S
G
S
G
P
V
Y
V
S
G
Q
Zebra Danio
Brachydanio rerio
XP_001923962
485
53928
E295
Y
D
S
D
E
R
K
E
T
S
C
E
H
H
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122793
483
53108
S294
L
S
P
T
H
S
I
S
E
I
M
Q
F
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781457
717
77816
A464
M
K
D
R
N
V
D
A
D
S
Q
L
N
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
48.2
99.2
N.A.
95.8
49.6
N.A.
42.5
92.7
20.8
65.3
N.A.
N.A.
20.6
N.A.
25.8
Protein Similarity:
100
99.8
65.7
100
N.A.
98
64.9
N.A.
57.2
96.4
32.2
75
N.A.
N.A.
37.2
N.A.
40.1
P-Site Identity:
100
100
0
100
N.A.
100
0
N.A.
0
93.3
6.6
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
0
100
N.A.
100
0
N.A.
6.6
93.3
13.3
6.6
N.A.
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
17
0
0
42
9
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
9
9
0
0
9
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
9
17
0
17
25
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
34
0
17
0
17
9
0
9
42
0
0
0
42
25
0
% G
% His:
0
0
0
0
9
0
9
0
0
0
0
0
9
9
0
% H
% Ile:
0
0
0
42
0
0
9
0
0
9
0
0
0
9
0
% I
% Lys:
0
9
0
9
0
0
9
0
0
0
0
0
0
9
0
% K
% Leu:
17
42
9
0
9
9
0
17
0
0
9
9
0
9
50
% L
% Met:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
9
9
0
0
9
0
9
% N
% Pro:
0
0
9
9
42
0
0
0
9
17
0
9
9
0
9
% P
% Gln:
9
9
0
0
0
0
0
0
0
0
9
9
0
0
9
% Q
% Arg:
25
25
0
9
0
9
17
0
0
0
42
42
9
42
0
% R
% Ser:
0
9
50
0
9
50
9
50
9
17
0
0
9
0
0
% S
% Thr:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
50
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
17
% W
% Tyr:
9
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _