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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRS2
All Species:
19.7
Human Site:
S428
Identified Species:
39.39
UniProt:
Q8WU20
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU20
NP_001036020.1
508
57029
S428
N
F
D
I
R
R
P
S
L
E
H
R
Q
L
N
Chimpanzee
Pan troglodytes
XP_522464
508
57026
S428
N
F
D
I
R
R
P
S
L
E
H
R
Q
L
N
Rhesus Macaque
Macaca mulatta
XP_001084538
492
54416
P412
R
R
P
G
P
E
P
P
R
Q
L
N
Y
I
Q
Dog
Lupus familis
XP_850500
508
57011
S428
N
F
D
I
R
R
P
S
L
E
H
R
Q
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8C180
508
56775
S428
N
F
D
I
R
R
P
S
L
E
H
R
Q
L
N
Rat
Rattus norvegicus
Q52RG8
492
54329
P412
R
R
P
G
P
E
P
P
R
Q
L
N
Y
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518131
552
59439
N472
P
G
Q
P
R
Q
L
N
Y
V
Q
V
E
L
K
Chicken
Gallus gallus
XP_416087
508
57269
S428
N
F
D
I
R
R
P
S
L
E
H
R
Q
L
N
Frog
Xenopus laevis
P07222
299
33514
T219
A
L
S
T
T
Q
K
T
P
K
T
P
E
Q
K
Zebra Danio
Brachydanio rerio
XP_001923962
485
53928
G405
D
L
R
R
L
G
V
G
D
P
L
R
Q
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122793
483
53108
L404
T
K
D
V
P
M
N
L
P
L
D
G
P
S
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781457
717
77816
S574
E
V
S
R
G
S
C
S
P
V
D
H
N
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
48.2
99.2
N.A.
95.8
49.6
N.A.
42.5
92.7
20.8
65.3
N.A.
N.A.
20.6
N.A.
25.8
Protein Similarity:
100
99.8
65.7
100
N.A.
98
64.9
N.A.
57.2
96.4
32.2
75
N.A.
N.A.
37.2
N.A.
40.1
P-Site Identity:
100
100
6.6
100
N.A.
100
6.6
N.A.
13.3
100
0
26.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
100
20
N.A.
33.3
100
26.6
33.3
N.A.
N.A.
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
50
0
0
0
0
0
9
0
17
0
0
0
0
% D
% Glu:
9
0
0
0
0
17
0
0
0
42
0
0
17
0
0
% E
% Phe:
0
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
17
9
9
0
9
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
42
9
0
0
0
% H
% Ile:
0
0
0
42
0
0
0
0
0
0
0
0
0
17
0
% I
% Lys:
0
9
0
0
0
0
9
0
0
9
0
0
0
0
17
% K
% Leu:
0
17
0
0
9
0
9
9
42
9
25
0
0
59
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
42
0
0
0
0
0
9
9
0
0
0
17
9
0
59
% N
% Pro:
9
0
17
9
25
0
59
17
25
9
0
9
9
0
0
% P
% Gln:
0
0
9
0
0
17
0
0
0
17
9
0
50
9
17
% Q
% Arg:
17
17
9
17
50
42
0
0
17
0
0
50
0
0
0
% R
% Ser:
0
0
17
0
0
9
0
50
0
0
0
0
0
9
0
% S
% Thr:
9
0
0
9
9
0
0
9
0
0
9
0
0
0
0
% T
% Val:
0
9
0
9
0
0
9
0
0
17
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
17
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _