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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABHD3 All Species: 13.64
Human Site: Y18 Identified Species: 21.43
UniProt: Q8WU67 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WU67 NP_612213.2 409 46009 Y18 L S R E L S L Y L E H Q V R V
Chimpanzee Pan troglodytes XP_525719 405 45186 S18 G T W A D T F S L L L A L A V
Rhesus Macaque Macaca mulatta XP_001090188 405 45067 S18 G T W A D T F S L P L A L A V
Dog Lupus familis XP_537301 393 44314 E15 R E L S L Y L E H H V R V G F
Cat Felis silvestris
Mouse Mus musculus Q91ZH7 411 46214 Y18 L S R E L A L Y L E H Q V R V
Rat Rattus norvegicus Q5RK23 412 45539 Q17 L S S S L S P Q N G T W S D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507042 413 47047 F18 A V S M P S L F S C P L T L R
Chicken Gallus gallus XP_419156 406 45949 L14 T R E L S L Y L E S Q V R V G
Frog Xenopus laevis NP_001089426 410 45908 Y17 L T R D L S L Y L E N Q V R V
Zebra Danio Brachydanio rerio Q802V6 432 48655 F19 A P E M P A M F D G M K L A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24093 398 45383 C14 T L I A V I V C I L F R I L N
Honey Bee Apis mellifera XP_624134 393 44041 Y15 L L D I P V V Y Y G A L L G V
Nematode Worm Caenorhab. elegans Q18610 375 42318
Sea Urchin Strong. purpuratus XP_789299 395 44144 W15 M I T A Y Q H W R T A A V C V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03649 449 51419 K29 I A F K S T D K R E N E N K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.2 44.9 91.9 N.A. 92.9 46.3 N.A. 58.5 79.9 72.9 23.1 N.A. 24.9 38.6 30 41
Protein Similarity: 100 66.7 66 92.9 N.A. 96.5 66 N.A. 66.5 87.7 85.3 44.2 N.A. 46.2 61.6 50.8 59.1
P-Site Identity: 100 13.3 13.3 20 N.A. 93.3 26.6 N.A. 13.3 0 80 0 N.A. 0 20 0 13.3
P-Site Similarity: 100 33.3 33.3 26.6 N.A. 100 26.6 N.A. 20 0 100 33.3 N.A. 33.3 33.3 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 0 27 0 14 0 0 0 0 14 20 0 20 14 % A
% Cys: 0 0 0 0 0 0 0 7 0 7 0 0 0 7 0 % C
% Asp: 0 0 7 7 14 0 7 0 7 0 0 0 0 7 0 % D
% Glu: 0 7 14 14 0 0 0 7 7 27 0 7 0 0 7 % E
% Phe: 0 0 7 0 0 0 14 14 0 0 7 0 0 0 7 % F
% Gly: 14 0 0 0 0 0 0 0 0 20 0 0 0 14 7 % G
% His: 0 0 0 0 0 0 7 0 7 7 14 0 0 0 0 % H
% Ile: 7 7 7 7 0 7 0 0 7 0 0 0 7 0 0 % I
% Lys: 0 0 0 7 0 0 0 7 0 0 0 7 0 7 0 % K
% Leu: 34 14 7 7 34 7 34 7 34 14 14 14 27 14 0 % L
% Met: 7 0 0 14 0 0 7 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 14 0 7 0 7 % N
% Pro: 0 7 0 0 20 0 7 0 0 7 7 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 7 0 0 7 20 0 0 0 % Q
% Arg: 7 7 20 0 0 0 0 0 14 0 0 14 7 20 7 % R
% Ser: 0 20 14 14 14 27 0 14 7 7 0 0 7 0 0 % S
% Thr: 14 20 7 0 0 20 0 0 0 7 7 0 7 0 0 % T
% Val: 0 7 0 0 7 7 14 0 0 0 7 7 34 7 47 % V
% Trp: 0 0 14 0 0 0 0 7 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 7 7 7 27 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _