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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABHD3
All Species:
17.58
Human Site:
Y322
Identified Species:
27.62
UniProt:
Q8WU67
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU67
NP_612213.2
409
46009
Y322
Y
Q
T
I
D
D
Y
Y
T
D
A
S
P
S
P
Chimpanzee
Pan troglodytes
XP_525719
405
45186
R318
R
T
K
I
D
A
I
R
I
P
V
L
C
L
N
Rhesus Macaque
Macaca mulatta
XP_001090188
405
45067
R318
R
T
K
V
D
A
I
R
I
P
V
L
C
L
N
Dog
Lupus familis
XP_537301
393
44314
R311
Y
T
D
A
S
P
N
R
R
L
K
S
V
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZH7
411
46214
Y322
Y
R
T
L
D
D
Y
Y
T
D
A
S
P
N
R
Rat
Rattus norvegicus
Q5RK23
412
45539
Y313
Y
K
D
C
A
A
Y
Y
H
A
S
S
P
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507042
413
47047
G330
V
R
A
V
V
E
H
G
H
E
L
S
P
K
I
Chicken
Gallus gallus
XP_419156
406
45949
Y317
Y
R
T
I
D
D
Y
Y
E
D
A
S
P
C
R
Frog
Xenopus laevis
NP_001089426
410
45908
Y321
Y
P
T
N
E
H
Y
Y
R
D
A
S
P
C
H
Zebra Danio
Brachydanio rerio
Q802V6
432
48655
Y322
H
N
S
L
K
E
Y
Y
E
K
E
S
C
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24093
398
45383
F313
W
S
S
S
L
F
Y
F
D
T
I
K
K
P
M
Honey Bee
Apis mellifera
XP_624134
393
44041
L312
N
A
T
I
H
D
K
L
H
L
I
D
V
P
L
Nematode Worm
Caenorhab. elegans
Q18610
375
42318
A294
C
D
D
Y
Y
R
Q
A
T
L
A
T
K
V
D
Sea Urchin
Strong. purpuratus
XP_789299
395
44144
L313
S
S
S
P
R
G
K
L
S
K
I
T
V
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03649
449
51419
Y340
Y
K
N
A
E
E
Y
Y
K
N
A
S
S
Y
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.2
44.9
91.9
N.A.
92.9
46.3
N.A.
58.5
79.9
72.9
23.1
N.A.
24.9
38.6
30
41
Protein Similarity:
100
66.7
66
92.9
N.A.
96.5
66
N.A.
66.5
87.7
85.3
44.2
N.A.
46.2
61.6
50.8
59.1
P-Site Identity:
100
13.3
6.6
13.3
N.A.
73.3
33.3
N.A.
13.3
73.3
53.3
20
N.A.
6.6
20
13.3
0
P-Site Similarity:
100
13.3
13.3
13.3
N.A.
93.3
46.6
N.A.
46.6
80
60
46.6
N.A.
26.6
20
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
14
7
20
0
7
0
7
40
0
0
0
0
% A
% Cys:
7
0
0
7
0
0
0
0
0
0
0
0
20
14
0
% C
% Asp:
0
7
20
0
34
27
0
0
7
27
0
7
0
0
7
% D
% Glu:
0
0
0
0
14
20
0
0
14
7
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
7
0
0
0
0
0
7
0
% G
% His:
7
0
0
0
7
7
7
0
20
0
0
0
0
0
14
% H
% Ile:
0
0
0
27
0
0
14
0
14
0
20
0
0
0
14
% I
% Lys:
0
14
14
0
7
0
14
0
7
14
7
7
14
7
7
% K
% Leu:
0
0
0
14
7
0
0
14
0
20
7
14
0
14
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
7
7
7
0
0
7
0
0
7
0
0
0
7
14
% N
% Pro:
0
7
0
7
0
7
0
0
0
14
0
0
40
20
7
% P
% Gln:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
14
20
0
0
7
7
0
20
14
0
0
0
0
7
14
% R
% Ser:
7
14
20
7
7
0
0
0
7
0
7
60
7
7
0
% S
% Thr:
0
20
34
0
0
0
0
0
20
7
0
14
0
0
14
% T
% Val:
7
0
0
14
7
0
0
0
0
0
14
0
20
14
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
47
0
0
7
7
0
54
47
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _