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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: U2AF1L4 All Species: 27.27
Human Site: S65 Identified Species: 54.55
UniProt: Q8WU68 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WU68 NP_001035515.1 220 25744 S65 T A Q T A D G S H C H V S D V
Chimpanzee Pan troglodytes XP_001160916 220 25675 S65 T A Q T A D G S H C H V S D V
Rhesus Macaque Macaca mulatta XP_001112161 216 25287 S65 T A Q T A D G S H C H V S D V
Dog Lupus familis XP_853689 220 25836 S65 T A Q T A D G S H C H V S D V
Cat Felis silvestris
Mouse Mus musculus Q9D883 239 27796 L65 S S Q S A D G L R C A V S D V
Rat Rattus norvegicus Q7TP17 220 25817 S65 T A Q T A D G S H C H V S D V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511817 308 34702 S123 S A Q T A D G S H L L G A V S
Chicken Gallus gallus
Frog Xenopus laevis NP_001089860 245 28258 L65 S S Q S A D G L R C A V S D V
Zebra Danio Brachydanio rerio NP_803432 249 28359 L65 T A Q S A D G L N A V S D V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q94535 264 29858 S65 S A K S A D G S H L V A N V S
Honey Bee Apis mellifera XP_397281 242 28274 S65 S A K S A D G S H L V A N V S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S709 296 34554 Q65 I T P G V D A Q G Q P L D P R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.1 91.3 94.5 N.A. 73.2 94 N.A. 55.5 N.A. 71.8 70.2 N.A. 61.7 67.3 N.A. N.A.
Protein Similarity: 100 99 93.6 96.3 N.A. 80.7 95.9 N.A. 62.3 N.A. 79.1 77.5 N.A. 71.9 76.4 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 60 100 N.A. 53.3 N.A. 60 40 N.A. 40 40 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 80 100 N.A. 66.6 N.A. 80 53.3 N.A. 66.6 66.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 41.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 55 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 75 0 0 92 0 9 0 0 9 17 17 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 100 0 0 0 0 0 0 17 59 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 92 0 9 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 67 0 42 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 25 0 25 9 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 0 17 0 0 % N
% Pro: 0 0 9 0 0 0 0 0 0 0 9 0 0 9 0 % P
% Gln: 0 0 75 0 0 0 0 9 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 9 % R
% Ser: 42 17 0 42 0 0 0 67 0 0 0 9 59 0 25 % S
% Thr: 50 9 0 50 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 25 59 0 34 59 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _