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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCFD2 All Species: 4.24
Human Site: S205 Identified Species: 9.33
UniProt: Q8WU76 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WU76 NP_689753.2 684 75127 S205 G S L G D V D S T T L T P E L
Chimpanzee Pan troglodytes XP_001148032 684 75180 S205 G S L G D V D S T A L T P E L
Rhesus Macaque Macaca mulatta XP_001091758 684 75345 A205 G S L G D V D A T A L T P E L
Dog Lupus familis XP_849695 683 74856 A204 G S L S E V D A A A L P P E L
Cat Felis silvestris
Mouse Mus musculus Q8BTY8 684 74732 A205 S S L G E V D A T A L T P E L
Rat Rattus norvegicus NP_001017499 684 74776 A205 N S L G E V D A T A L T P E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233406 514 56013 E65 G A M G V R E E C F A V G A L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001013582 582 64051 C133 E Q F E E K L C E W M G D M N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625059 640 72800 D181 G D L M P P L D T N I L K D M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783509 657 72481 I206 E S V S D V D I S M L P D E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_181798 838 91684 E216 P S Q G S V A E A S L S R Q H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 96.6 89 N.A. 83.4 85 N.A. N.A. 51.4 N.A. 45.4 N.A. N.A. 21.2 N.A. 38.4
Protein Similarity: 100 99.2 98.5 94.4 N.A. 91.8 92.2 N.A. N.A. 60.8 N.A. 60.5 N.A. N.A. 46.2 N.A. 58.6
P-Site Identity: 100 93.3 86.6 60 N.A. 73.3 73.3 N.A. N.A. 20 N.A. 0 N.A. N.A. 20 N.A. 46.6
P-Site Similarity: 100 93.3 93.3 73.3 N.A. 86.6 86.6 N.A. N.A. 40 N.A. 13.3 N.A. N.A. 40 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 10 37 19 46 10 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 37 0 64 10 0 0 0 0 19 10 0 % D
% Glu: 19 0 0 10 37 0 10 19 10 0 0 0 0 64 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 55 0 0 64 0 0 0 0 0 0 0 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 64 0 0 0 19 0 0 0 73 10 0 0 73 % L
% Met: 0 0 10 10 0 0 0 0 0 10 10 0 0 10 10 % M
% Asn: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % N
% Pro: 10 0 0 0 10 10 0 0 0 0 0 19 55 0 0 % P
% Gln: 0 10 10 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % R
% Ser: 10 73 0 19 10 0 0 19 10 10 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 55 10 0 46 0 0 0 % T
% Val: 0 0 10 0 10 73 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _