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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCFD2
All Species:
6.67
Human Site:
S552
Identified Species:
14.67
UniProt:
Q8WU76
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU76
NP_689753.2
684
75127
S552
R
D
I
A
G
A
R
S
L
L
K
Q
F
K
S
Chimpanzee
Pan troglodytes
XP_001148032
684
75180
S552
R
D
I
A
G
A
R
S
L
L
K
Q
F
K
S
Rhesus Macaque
Macaca mulatta
XP_001091758
684
75345
N552
R
D
I
A
G
A
R
N
L
M
K
Q
F
K
S
Dog
Lupus familis
XP_849695
683
74856
N551
R
D
I
A
G
A
R
N
L
M
K
Q
F
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTY8
684
74732
N552
R
E
I
A
G
A
R
N
L
M
R
Q
F
K
S
Rat
Rattus norvegicus
NP_001017499
684
74776
N552
R
E
I
A
G
A
R
N
L
L
R
Q
F
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233406
514
56013
N388
R
T
H
M
K
Q
F
N
S
I
H
N
P
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013582
582
64051
S456
S
S
E
S
G
T
G
S
D
L
S
M
D
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625059
640
72800
R513
L
R
L
V
A
E
Q
R
L
I
L
Q
D
Y
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783509
657
72481
K531
R
S
E
A
T
A
Q
K
V
A
K
E
I
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181798
838
91684
S704
F
R
F
L
H
K
L
S
S
L
R
T
R
N
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
96.6
89
N.A.
83.4
85
N.A.
N.A.
51.4
N.A.
45.4
N.A.
N.A.
21.2
N.A.
38.4
Protein Similarity:
100
99.2
98.5
94.4
N.A.
91.8
92.2
N.A.
N.A.
60.8
N.A.
60.5
N.A.
N.A.
46.2
N.A.
58.6
P-Site Identity:
100
100
86.6
86.6
N.A.
73.3
80
N.A.
N.A.
13.3
N.A.
20
N.A.
N.A.
13.3
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
26.6
N.A.
26.6
N.A.
N.A.
33.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
64
10
64
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
37
0
0
0
0
0
0
10
0
0
0
19
10
0
% D
% Glu:
0
19
19
0
0
10
0
0
0
0
0
10
0
0
0
% E
% Phe:
10
0
10
0
0
0
10
0
0
0
0
0
55
0
0
% F
% Gly:
0
0
0
0
64
0
10
0
0
0
0
0
0
10
0
% G
% His:
0
0
10
0
10
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
55
0
0
0
0
0
0
19
0
0
10
0
0
% I
% Lys:
0
0
0
0
10
10
0
10
0
0
46
0
0
55
0
% K
% Leu:
10
0
10
10
0
0
10
0
64
46
10
0
0
0
19
% L
% Met:
0
0
0
10
0
0
0
0
0
28
0
10
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
46
0
0
0
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
10
19
0
0
0
0
64
0
0
0
% Q
% Arg:
73
19
0
0
0
0
55
10
0
0
28
0
10
0
10
% R
% Ser:
10
19
0
10
0
0
0
37
19
0
10
0
0
0
73
% S
% Thr:
0
10
0
0
10
10
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _