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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCFD2
All Species:
20
Human Site:
S571
Identified Species:
44
UniProt:
Q8WU76
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU76
NP_689753.2
684
75127
S571
G
N
H
T
H
Q
A
S
Y
K
P
L
L
K
Q
Chimpanzee
Pan troglodytes
XP_001148032
684
75180
S571
G
N
H
T
H
Q
A
S
Y
K
P
L
L
K
Q
Rhesus Macaque
Macaca mulatta
XP_001091758
684
75345
S571
G
N
H
T
H
Q
A
S
Y
K
P
L
L
K
Q
Dog
Lupus familis
XP_849695
683
74856
S570
G
N
H
T
H
Q
A
S
Y
K
P
L
L
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTY8
684
74732
S571
G
N
N
T
H
Q
A
S
Y
K
P
L
L
K
Q
Rat
Rattus norvegicus
NP_001017499
684
74776
A571
G
N
S
T
H
Q
A
A
Y
K
P
L
L
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233406
514
56013
K407
A
S
Y
K
P
L
L
K
Q
V
V
E
E
I
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013582
582
64051
K475
V
Y
V
Y
S
V
A
K
E
A
C
S
G
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625059
640
72800
I532
K
P
S
S
Q
E
V
I
R
H
I
S
I
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783509
657
72481
L550
I
S
R
A
R
N
T
L
Q
R
F
M
D
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181798
838
91684
S723
G
S
L
A
S
E
S
S
F
P
G
E
P
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
96.6
89
N.A.
83.4
85
N.A.
N.A.
51.4
N.A.
45.4
N.A.
N.A.
21.2
N.A.
38.4
Protein Similarity:
100
99.2
98.5
94.4
N.A.
91.8
92.2
N.A.
N.A.
60.8
N.A.
60.5
N.A.
N.A.
46.2
N.A.
58.6
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
13.3
N.A.
6.6
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
19
0
0
64
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
19
0
0
10
0
0
19
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% F
% Gly:
64
0
0
0
0
0
0
0
0
0
10
0
10
10
10
% G
% His:
0
0
37
0
55
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
10
0
10
10
0
% I
% Lys:
10
0
0
10
0
0
0
19
0
55
0
0
0
55
0
% K
% Leu:
0
0
10
0
0
10
10
10
0
0
0
55
55
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
55
10
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
10
0
0
0
0
10
55
0
10
0
0
% P
% Gln:
0
0
0
0
10
55
0
0
19
0
0
0
0
0
55
% Q
% Arg:
0
0
10
0
10
0
0
0
10
10
0
0
0
0
0
% R
% Ser:
0
28
19
10
19
0
10
55
0
0
0
19
0
10
10
% S
% Thr:
0
0
0
55
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
10
0
10
0
0
10
10
0
0
10
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
10
0
0
0
0
55
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _