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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCFD2
All Species:
20
Human Site:
T486
Identified Species:
44
UniProt:
Q8WU76
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU76
NP_689753.2
684
75127
T486
Y
S
V
T
G
E
L
T
V
D
K
D
L
C
E
Chimpanzee
Pan troglodytes
XP_001148032
684
75180
T486
Y
S
V
T
G
E
L
T
V
D
K
D
L
C
E
Rhesus Macaque
Macaca mulatta
XP_001091758
684
75345
T486
Y
S
V
T
G
E
L
T
V
D
K
D
L
D
E
Dog
Lupus familis
XP_849695
683
74856
T485
Y
S
V
S
G
E
F
T
V
D
K
D
L
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTY8
684
74732
T486
Y
S
V
P
G
D
V
T
L
D
R
D
L
G
D
Rat
Rattus norvegicus
NP_001017499
684
74776
T486
Y
S
V
T
G
E
C
T
R
D
T
D
L
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233406
514
56013
A331
A
E
E
E
V
K
K
A
L
V
K
A
I
C
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013582
582
64051
L399
L
E
S
H
S
G
V
L
Q
L
G
L
A
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625059
640
72800
A456
L
E
K
S
I
A
N
A
I
F
E
D
L
Q
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783509
657
72481
V474
S
Y
S
L
E
E
V
V
Q
L
I
L
Y
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181798
838
91684
P614
V
D
A
V
L
E
N
P
S
A
G
N
L
K
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
96.6
89
N.A.
83.4
85
N.A.
N.A.
51.4
N.A.
45.4
N.A.
N.A.
21.2
N.A.
38.4
Protein Similarity:
100
99.2
98.5
94.4
N.A.
91.8
92.2
N.A.
N.A.
60.8
N.A.
60.5
N.A.
N.A.
46.2
N.A.
58.6
P-Site Identity:
100
100
93.3
80
N.A.
53.3
66.6
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
73.3
N.A.
N.A.
40
N.A.
6.6
N.A.
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
10
0
19
0
10
0
10
10
10
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
28
0
% C
% Asp:
0
10
0
0
0
10
0
0
0
55
0
64
0
10
28
% D
% Glu:
0
28
10
10
10
64
0
0
0
0
10
0
0
0
37
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
10
% F
% Gly:
0
0
0
0
55
10
0
0
0
0
19
0
0
37
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
10
0
10
0
10
0
10
% I
% Lys:
0
0
10
0
0
10
10
0
0
0
46
0
0
10
0
% K
% Leu:
19
0
0
10
10
0
28
10
19
19
0
19
73
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
19
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
19
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% R
% Ser:
10
55
19
19
10
0
0
0
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
37
0
0
0
55
0
0
10
0
0
0
0
% T
% Val:
10
0
55
10
10
0
28
10
37
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
55
10
0
0
0
0
0
0
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _