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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMAP2 All Species: 29.09
Human Site: S270 Identified Species: 49.23
UniProt: Q8WU79 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WU79 NP_073570.1 429 46786 S270 L S K D S I L S L Y G S Q T P
Chimpanzee Pan troglodytes XP_513355 607 63762 S448 L S K D S I L S L Y G S Q T P
Rhesus Macaque Macaca mulatta XP_001083189 660 69891 S501 L S K D S I L S L Y G S Q T P
Dog Lupus familis XP_539575 405 44009 S246 L S K D S I L S L Y G S Q T P
Cat Felis silvestris
Mouse Mus musculus Q7TN29 428 46559 S269 L S K D S I L S L Y G S Q T P
Rat Rattus norvegicus NP_001094139 428 46475 S269 L S K D S I L S L Y G S Q T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507351 431 46646 S270 L S K D S I L S L Y G S Q T P
Chicken Gallus gallus Q5F413 428 46296 Y269 K D S I L S L Y G S Q T P Q L
Frog Xenopus laevis NP_001086060 421 45767 G254 G G K S E D G G K K Q L S K D
Zebra Danio Brachydanio rerio NP_001038260 418 45253 D259 S G K K L S K D S I L S L Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610424 517 55013 A323 M S K D S I L A L Y G S A P A
Honey Bee Apis mellifera XP_623142 486 53406 L283 K M S K D S I L A L Y G T S S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FL69 483 52574 S291 S S P P A S S S D F E D L F K
Baker's Yeast Sacchar. cerevisiae P40529 298 32620 L140 N D S T E P V L H K P S A N H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.8 62.8 89.9 N.A. 95.5 95.5 N.A. 82.5 79.4 67.8 57.8 N.A. 32.6 33.7 N.A. N.A.
Protein Similarity: 100 69.1 63.4 92.7 N.A. 96.5 96.2 N.A. 90.2 88.5 78.7 69 N.A. 45.4 49.1 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 6.6 6.6 13.3 N.A. 66.6 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 13.3 6.6 13.3 N.A. 80 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.1 27.7 N.A.
Protein Similarity: N.A. N.A. N.A. 44.9 41.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 8 0 0 0 15 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 58 8 8 0 8 8 0 0 8 0 0 8 % D
% Glu: 0 0 0 0 15 0 0 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % F
% Gly: 8 15 0 0 0 0 8 8 8 0 58 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % H
% Ile: 0 0 0 8 0 58 8 0 0 8 0 0 0 0 0 % I
% Lys: 15 0 72 15 0 0 8 0 8 15 0 0 0 8 8 % K
% Leu: 50 0 0 0 15 0 65 15 58 8 8 8 15 0 8 % L
% Met: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 8 8 0 8 0 0 0 0 8 0 8 8 50 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 15 0 50 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 15 65 22 8 58 29 8 58 8 8 0 72 8 8 15 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 0 8 8 50 0 % T
% Val: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 58 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _