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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMAP2 All Species: 19.7
Human Site: S312 Identified Species: 33.33
UniProt: Q8WU79 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WU79 NP_073570.1 429 46786 S312 P P N S I M G S M M P P P V G
Chimpanzee Pan troglodytes XP_513355 607 63762 S490 P P N S I M G S M M P P P V G
Rhesus Macaque Macaca mulatta XP_001083189 660 69891 S543 P P N S I M G S M M P P P V G
Dog Lupus familis XP_539575 405 44009 S288 P P N S I M G S M M P P P V G
Cat Felis silvestris
Mouse Mus musculus Q7TN29 428 46559 G311 P P N S I M G G M V P P P V G
Rat Rattus norvegicus NP_001094139 428 46475 S311 P P N S I M G S M M P P P V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507351 431 46646 G312 T P P G N M I G G M M P P P V
Chicken Gallus gallus Q5F413 428 46296 G311 P S S S M M G G M M A P S V G
Frog Xenopus laevis NP_001086060 421 45767 F296 Y P N A Y P G F S A V P S P G
Zebra Danio Brachydanio rerio NP_001038260 418 45253 L301 G Y G Q Y Q A L G A Q Q G M M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610424 517 55013 P365 I P H Q F M T P P N S V S M Y
Honey Bee Apis mellifera XP_623142 486 53406 T325 V V P F G Q Q T S F P N Q Q S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FL69 483 52574 Q333 V S P F A M H Q Q Q V A M L A
Baker's Yeast Sacchar. cerevisiae P40529 298 32620 T182 L S T S R S N T S L L N L Q V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.8 62.8 89.9 N.A. 95.5 95.5 N.A. 82.5 79.4 67.8 57.8 N.A. 32.6 33.7 N.A. N.A.
Protein Similarity: 100 69.1 63.4 92.7 N.A. 96.5 96.2 N.A. 90.2 88.5 78.7 69 N.A. 45.4 49.1 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 100 N.A. 33.3 60 33.3 0 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 33.3 73.3 40 6.6 N.A. 26.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.1 27.7 N.A.
Protein Similarity: N.A. N.A. N.A. 44.9 41.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 8 0 0 15 8 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 15 8 0 0 8 0 8 0 0 0 0 0 % F
% Gly: 8 0 8 8 8 0 58 22 15 0 0 0 8 0 58 % G
% His: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 43 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 0 0 8 0 8 8 0 8 8 0 % L
% Met: 0 0 0 0 8 72 0 0 50 50 8 0 8 15 8 % M
% Asn: 0 0 50 0 8 0 8 0 0 8 0 15 0 0 0 % N
% Pro: 50 65 22 0 0 8 0 8 8 0 50 65 50 15 0 % P
% Gln: 0 0 0 15 0 15 8 8 8 8 8 8 8 15 0 % Q
% Arg: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 22 8 58 0 8 0 36 22 0 8 0 22 0 8 % S
% Thr: 8 0 8 0 0 0 8 15 0 0 0 0 0 0 0 % T
% Val: 15 8 0 0 0 0 0 0 0 8 15 8 0 50 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 15 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _