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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3H15
All Species:
44.55
Human Site:
T176
Identified Species:
70
UniProt:
Q8WU90
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU90
NP_060941.2
426
48602
T176
A
E
K
K
K
P
K
T
Q
I
V
C
K
H
F
Chimpanzee
Pan troglodytes
XP_001174233
426
48773
T176
A
E
K
K
K
P
K
T
Q
I
V
C
K
H
F
Rhesus Macaque
Macaca mulatta
XP_001103920
426
48580
T176
A
E
K
K
K
P
K
T
Q
I
V
C
K
H
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3TIV5
426
48309
T176
A
E
K
K
K
P
K
T
Q
I
V
C
R
H
F
Rat
Rattus norvegicus
Q6U6G5
426
48281
T176
A
E
K
K
K
P
K
T
Q
I
V
C
R
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516001
491
55349
T240
A
E
K
K
K
P
K
T
Q
I
V
C
K
H
F
Chicken
Gallus gallus
Q5H7N8
429
48978
T177
A
E
K
K
K
P
K
T
Q
I
V
C
K
Y
F
Frog
Xenopus laevis
Q6DD06
426
48694
T177
A
E
K
I
K
A
K
T
Q
I
V
C
K
F
F
Zebra Danio
Brachydanio rerio
Q803J8
433
49196
T177
A
E
K
K
K
A
K
T
Q
I
V
C
K
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JWR9
404
45273
T167
G
E
K
Q
R
P
T
T
D
I
I
C
K
F
F
Honey Bee
Apis mellifera
XP_392829
398
45595
T170
G
S
G
N
R
P
T
T
D
I
I
C
K
H
F
Nematode Worm
Caenorhab. elegans
Q93618
374
43283
I163
K
N
K
N
K
H
M
I
D
I
V
C
K
Y
F
Sea Urchin
Strong. purpuratus
XP_785608
416
46905
T166
A
N
E
S
K
T
K
T
E
I
V
C
R
F
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SK74
371
42371
N153
K
V
V
E
S
K
K
N
E
Y
N
Q
N
K
P
Baker's Yeast
Sacchar. cerevisiae
Q12000
345
39496
D135
T
R
S
E
K
E
N
D
T
M
D
N
W
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99.7
N.A.
N.A.
95.5
96.4
N.A.
77.8
87.1
78.4
76.9
N.A.
53.5
56.8
43.9
50.7
Protein Similarity:
100
99
99.7
N.A.
N.A.
97.6
97.8
N.A.
81.6
93.2
86.8
87
N.A.
68
70.1
64.5
68.5
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
100
93.3
80
86.6
N.A.
53.3
46.6
46.6
53.3
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
100
80
93.3
N.A.
73.3
60
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.2
37.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.8
52.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
87
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
20
0
7
0
0
7
0
% D
% Glu:
0
67
7
14
0
7
0
0
14
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
87
% F
% Gly:
14
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
47
0
% H
% Ile:
0
0
0
7
0
0
0
7
0
87
14
0
0
0
0
% I
% Lys:
14
0
74
54
80
7
74
0
0
0
0
0
67
7
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% M
% Asn:
0
14
0
14
0
0
7
7
0
0
7
7
7
0
0
% N
% Pro:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
7
0
0
0
0
60
0
0
7
0
0
0
% Q
% Arg:
0
7
0
0
14
0
0
0
0
0
0
0
20
0
0
% R
% Ser:
0
7
7
7
7
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
7
14
80
7
0
0
0
0
0
0
% T
% Val:
0
7
7
0
0
0
0
0
0
0
74
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _