KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D22A
All Species:
13.64
Human Site:
S167
Identified Species:
33.33
UniProt:
Q8WUA7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA7
NP_055161.1
517
59121
S167
A
P
L
Q
R
S
Q
S
L
P
H
S
A
T
V
Chimpanzee
Pan troglodytes
XP_515210
517
59021
S167
A
P
L
Q
R
S
Q
S
L
P
H
S
A
T
V
Rhesus Macaque
Macaca mulatta
XP_001112840
308
36544
Dog
Lupus familis
XP_848590
517
59090
S167
V
P
L
Q
R
S
Q
S
L
P
H
S
V
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5A6
516
59344
S166
V
P
L
Q
R
S
Q
S
L
P
H
S
A
T
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509397
560
64265
I160
I
I
P
L
V
A
R
I
S
D
Q
N
A
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394268
546
62868
T188
A
S
P
Q
H
K
P
T
Q
F
P
G
R
P
Q
Nematode Worm
Caenorhab. elegans
NP_001023165
495
56525
R164
T
R
F
A
R
L
R
R
L
F
S
N
G
K
S
Sea Urchin
Strong. purpuratus
XP_797601
498
57012
K165
S
T
I
P
F
S
N
K
Q
D
E
K
A
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08484
637
73271
Q225
Y
P
Q
L
P
Q
L
Q
K
E
K
T
N
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
53.5
91.3
N.A.
89.9
N.A.
N.A.
54.6
N.A.
N.A.
N.A.
N.A.
N.A.
43.7
46.2
46.8
Protein Similarity:
100
98.8
55.9
95.5
N.A.
94.3
N.A.
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
N.A.
60.9
60.5
64
P-Site Identity:
100
100
0
86.6
N.A.
93.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
13.3
13.3
P-Site Similarity:
100
100
0
86.6
N.A.
93.3
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
10
0
10
0
0
0
0
0
0
50
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
20
0
0
0
20
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% E
% Phe:
0
0
10
0
10
0
0
0
0
20
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% G
% His:
0
0
0
0
10
0
0
0
0
0
40
0
0
0
0
% H
% Ile:
10
10
10
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
10
10
0
10
10
0
10
10
% K
% Leu:
0
0
40
20
0
10
10
0
50
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
20
10
0
0
% N
% Pro:
0
50
20
10
10
0
10
0
0
40
10
0
0
10
0
% P
% Gln:
0
0
10
50
0
10
40
10
20
0
10
0
0
0
10
% Q
% Arg:
0
10
0
0
50
0
20
10
0
0
0
0
10
0
0
% R
% Ser:
10
10
0
0
0
50
0
40
10
0
10
40
0
10
20
% S
% Thr:
10
10
0
0
0
0
0
10
0
0
0
10
0
40
0
% T
% Val:
20
0
0
0
10
0
0
0
0
0
0
0
10
0
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _