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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D22A
All Species:
8.48
Human Site:
S44
Identified Species:
20.74
UniProt:
Q8WUA7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA7
NP_055161.1
517
59121
S44
L
H
G
T
L
L
R
S
T
A
K
M
P
T
T
Chimpanzee
Pan troglodytes
XP_515210
517
59021
S44
L
H
G
T
L
L
R
S
T
A
K
M
P
A
T
Rhesus Macaque
Macaca mulatta
XP_001112840
308
36544
Dog
Lupus familis
XP_848590
517
59090
A44
L
H
G
T
L
L
K
A
T
P
K
A
P
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5A6
516
59344
S44
L
H
G
T
L
L
K
S
T
P
K
V
P
T
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509397
560
64265
K45
K
V
N
T
L
P
L
K
N
K
K
A
S
S
F
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394268
546
62868
I53
M
S
G
S
S
A
N
I
I
S
T
G
G
T
I
Nematode Worm
Caenorhab. elegans
NP_001023165
495
56525
E46
M
N
K
F
Q
D
Y
E
N
S
V
S
D
A
W
Sea Urchin
Strong. purpuratus
XP_797601
498
57012
D44
K
V
P
G
S
T
S
D
A
W
E
V
N
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08484
637
73271
A62
P
S
G
Y
A
S
S
A
D
R
D
R
R
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
53.5
91.3
N.A.
89.9
N.A.
N.A.
54.6
N.A.
N.A.
N.A.
N.A.
N.A.
43.7
46.2
46.8
Protein Similarity:
100
98.8
55.9
95.5
N.A.
94.3
N.A.
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
N.A.
60.9
60.5
64
P-Site Identity:
100
93.3
0
66.6
N.A.
80
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
0
0
P-Site Similarity:
100
93.3
0
86.6
N.A.
93.3
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
20
10
20
0
20
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
10
0
10
0
10
10
10
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
60
10
0
0
0
0
0
0
0
10
10
0
0
% G
% His:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% I
% Lys:
20
0
10
0
0
0
20
10
0
10
50
0
0
0
0
% K
% Leu:
40
0
0
0
50
40
10
0
0
0
0
0
0
0
0
% L
% Met:
20
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% M
% Asn:
0
10
10
0
0
0
10
0
20
0
0
0
10
0
0
% N
% Pro:
10
0
10
0
0
10
0
0
0
20
0
0
40
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
20
0
0
10
0
10
10
0
0
% R
% Ser:
0
20
0
10
20
10
20
30
0
20
0
10
10
20
10
% S
% Thr:
0
0
0
50
0
10
0
0
40
0
10
0
0
40
40
% T
% Val:
0
20
0
0
0
0
0
0
0
0
10
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% W
% Tyr:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _