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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSKU All Species: 20.3
Human Site: S331 Identified Species: 49.63
UniProt: Q8WUA8 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUA8 NP_056331.2 353 37807 S331 T Y P R R P G S S P K V A L H
Chimpanzee Pan troglodytes XP_508654 497 52842 S438 T Y P R R P G S S P K V A L H
Rhesus Macaque Macaca mulatta XP_001088364 353 37817 S331 A Y P R R P G S S P K V A L H
Dog Lupus familis XP_542296 357 38183 S335 A Y P R Q P G S S P K V A L H
Cat Felis silvestris
Mouse Mus musculus Q8CBR6 354 38344 S332 A Y H R Q P G S S P K V V L H
Rat Rattus norvegicus Q6QMY6 353 38072 S332 A Y H R Q P G S S P K V V L H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506133 403 42879 A376 Q Y H R Q Q E A A G L I R K E
Chicken Gallus gallus Q65Z91 369 40691 L330 Q Y H R Q I G L T K L G L G A
Frog Xenopus laevis NP_001089018 351 39000 K330 I F H A Q K G K V Q K E V L L
Zebra Danio Brachydanio rerio Q58A48 347 37757 F325 K T H M Q G Q F H R Q I G Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.6 96.8 86.2 N.A. 84.7 84.6 N.A. 51.8 52.5 48.4 48.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 70.4 98 90.4 N.A. 89.2 89.8 N.A. 63.2 70.4 67.7 63.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 73.3 73.3 N.A. 13.3 20 20 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 80 80 N.A. 40 33.3 33.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 0 10 0 0 0 10 10 0 0 0 40 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 10 % E
% Phe: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 80 0 0 10 0 10 10 10 0 % G
% His: 0 0 60 0 0 0 0 0 10 0 0 0 0 0 60 % H
% Ile: 10 0 0 0 0 10 0 0 0 0 0 20 0 0 0 % I
% Lys: 10 0 0 0 0 10 0 10 0 10 70 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 10 0 0 20 0 10 70 10 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 40 0 0 60 0 0 0 60 0 0 0 0 0 % P
% Gln: 20 0 0 0 70 10 10 0 0 10 10 0 0 10 0 % Q
% Arg: 0 0 0 80 30 0 0 0 0 10 0 0 10 0 0 % R
% Ser: 0 0 0 0 0 0 0 60 60 0 0 0 0 0 0 % S
% Thr: 20 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 60 30 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _