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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC12
All Species:
18.18
Human Site:
S149
Identified Species:
30.77
UniProt:
Q8WUD4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.54
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUD4
NP_653317
166
19181
S149
R
L
K
G
Q
E
D
S
L
A
S
A
V
D
A
Chimpanzee
Pan troglodytes
XP_001153411
166
19162
S149
R
L
K
G
Q
E
D
S
L
A
S
A
V
D
A
Rhesus Macaque
Macaca mulatta
XP_001113784
166
19146
S149
R
L
K
G
Q
D
D
S
L
A
S
A
V
D
A
Dog
Lupus familis
XP_541901
166
19037
S149
R
L
K
G
Q
E
D
S
L
A
S
A
V
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R344
166
18873
S149
R
L
K
G
Q
E
D
S
L
A
S
A
V
D
A
Rat
Rattus norvegicus
NP_001102253
166
18972
N149
R
L
K
G
Q
E
D
N
L
A
S
A
V
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521551
286
31987
D270
R
L
R
G
Q
D
E
D
L
A
S
A
V
G
S
Chicken
Gallus gallus
NP_001006353
175
19964
E159
R
L
K
G
Q
E
E
E
L
A
A
A
V
G
S
Frog
Xenopus laevis
NP_001091259
157
18263
E141
R
L
K
G
Q
E
E
E
L
A
T
A
V
A
S
Zebra Danio
Brachydanio rerio
NP_001003589
163
18466
E147
R
L
K
G
S
E
E
E
L
A
G
A
V
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651757
161
18264
A144
Q
M
E
D
I
S
Q
A
V
N
V
A
T
A
H
Honey Bee
Apis mellifera
XP_623598
153
17498
D136
R
L
K
Q
G
Q
H
D
L
A
A
V
V
N
M
Nematode Worm
Caenorhab. elegans
Q20334
250
28874
E233
V
I
E
P
V
E
E
E
E
T
A
A
S
E
G
Sea Urchin
Strong. purpuratus
XP_790871
181
20950
D157
L
Q
N
S
E
E
N
D
I
V
S
A
L
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
98.1
93.9
N.A.
90.3
90.3
N.A.
44
66.2
73.4
65.6
N.A.
43.3
53
21.6
44.2
Protein Similarity:
100
100
99.4
96.3
N.A.
93.3
93.9
N.A.
54.2
80.5
84.9
80.7
N.A.
62
69.2
39.5
61.3
P-Site Identity:
100
100
93.3
100
N.A.
100
93.3
N.A.
60
66.6
66.6
66.6
N.A.
6.6
40
13.3
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
86.6
86.6
73.3
N.A.
40
60
46.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
79
22
93
0
15
58
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
15
43
22
0
0
0
0
0
43
0
% D
% Glu:
0
0
15
0
8
72
36
29
8
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
72
8
0
0
0
0
0
8
0
0
22
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
8
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
72
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
79
0
0
0
0
0
0
79
0
0
0
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
8
8
0
8
0
0
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
8
65
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
79
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
8
8
0
36
0
0
58
0
8
0
22
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
8
0
8
8
0
% T
% Val:
8
0
0
0
8
0
0
0
8
8
8
8
79
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _