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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM172A All Species: 22.73
Human Site: Y86 Identified Species: 50
UniProt: Q8WUF8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUF8 NP_114431.2 416 47972 Y86 G E P F V F N Y R E D L H R W
Chimpanzee Pan troglodytes XP_001137302 370 42833 E57 K R Y E A L G E I I T K Y V Y
Rhesus Macaque Macaca mulatta XP_001090575 416 47980 Y86 G E P F V F N Y R E D L H R W
Dog Lupus familis XP_851856 474 53890 Y110 G E P F V F N Y R E D L H R W
Cat Felis silvestris
Mouse Mus musculus Q3TNH5 417 48054 Y86 G E P F V F N Y R E D L H R W
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509434 355 41030 D42 E P P L E F P D S L E G F E Y
Chicken Gallus gallus Q5ZK44 416 48335 Y86 G E P F V F N Y R E D L H R W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7T297 415 48190 Y84 G E P F V F N Y K E D L H R W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95RN0 325 36543 L12 L I Q I F R P L R S F R M S H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XW78 313 35293
Sea Urchin Strong. purpuratus XP_790439 454 51379 F106 G K P Y E F E F K K G N P M Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.4 99.5 74.8 N.A. 93 N.A. N.A. 77.6 87.5 N.A. 73.8 N.A. 32.2 N.A. 26.9 27
Protein Similarity: 100 88.9 99.7 78.9 N.A. 96.6 N.A. N.A. 82.6 94.2 N.A. 85 N.A. 46.8 N.A. 40.8 46.2
P-Site Identity: 100 0 100 100 N.A. 100 N.A. N.A. 13.3 100 N.A. 93.3 N.A. 6.6 N.A. 0 20
P-Site Similarity: 100 13.3 100 100 N.A. 100 N.A. N.A. 26.6 100 N.A. 100 N.A. 6.6 N.A. 0 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 55 0 0 0 0 % D
% Glu: 10 55 0 10 19 0 10 10 0 55 10 0 0 10 0 % E
% Phe: 0 0 0 55 10 73 0 10 0 0 10 0 10 0 0 % F
% Gly: 64 0 0 0 0 0 10 0 0 0 10 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 55 0 10 % H
% Ile: 0 10 0 10 0 0 0 0 10 10 0 0 0 0 0 % I
% Lys: 10 10 0 0 0 0 0 0 19 10 0 10 0 0 0 % K
% Leu: 10 0 0 10 0 10 0 10 0 10 0 55 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % M
% Asn: 0 0 0 0 0 0 55 0 0 0 0 10 0 0 0 % N
% Pro: 0 10 73 0 0 0 19 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 10 0 0 55 0 0 10 0 55 0 % R
% Ser: 0 0 0 0 0 0 0 0 10 10 0 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % T
% Val: 0 0 0 0 55 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55 % W
% Tyr: 0 0 10 10 0 0 0 55 0 0 0 0 10 0 28 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _