KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A17
All Species:
19.09
Human Site:
S297
Identified Species:
42
UniProt:
Q8WUG5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUG5
NP_057693.3
538
57686
S297
T
S
S
F
S
F
A
S
L
L
N
Y
R
N
I
Chimpanzee
Pan troglodytes
XP_001162356
538
57656
S297
T
S
S
F
S
F
A
S
L
L
N
Y
R
N
I
Rhesus Macaque
Macaca mulatta
XP_001107474
538
57655
S297
T
S
S
F
S
F
A
S
L
L
N
Y
R
N
I
Dog
Lupus familis
XP_850193
622
65650
S399
T
S
S
F
S
F
A
S
L
L
N
Y
R
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHH2
689
74306
R420
I
V
K
V
V
G
T
R
N
L
W
K
N
I
V
Rat
Rattus norvegicus
Q9P290
516
55377
S297
T
S
T
F
S
F
A
S
L
L
N
Y
R
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418968
691
75063
R430
I
I
K
V
V
G
T
R
N
L
W
K
N
I
V
Frog
Xenopus laevis
Q66J54
558
62434
E321
M
R
S
D
M
I
K
E
L
A
C
A
K
S
S
Zebra Danio
Brachydanio rerio
XP_002666780
546
59086
S331
F
T
E
L
D
S
E
S
S
S
S
P
T
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
F326
S
Q
P
A
A
T
V
F
D
L
L
R
Y
P
N
Honey Bee
Apis mellifera
XP_395856
579
65303
F345
D
F
K
K
P
S
L
F
D
L
F
R
Y
P
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
82.1
N.A.
27.8
93.1
N.A.
N.A.
28.3
22.5
40.8
N.A.
26.4
26.2
N.A.
N.A.
Protein Similarity:
100
99.8
99.6
82.4
N.A.
42.5
94.6
N.A.
N.A.
42.8
40.5
53.8
N.A.
42.7
42.1
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
93.3
N.A.
N.A.
6.6
13.3
6.6
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
13.3
100
N.A.
N.A.
13.3
26.6
20
N.A.
20
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
46
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
0
10
10
0
0
0
19
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
10
10
0
0
0
0
0
0
0
% E
% Phe:
10
10
0
46
0
46
0
19
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
10
0
0
0
10
0
0
0
0
0
0
0
19
46
% I
% Lys:
0
0
28
10
0
0
10
0
0
0
0
19
10
0
0
% K
% Leu:
0
0
0
10
0
0
10
0
55
82
10
0
0
0
0
% L
% Met:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
19
0
46
0
19
46
19
% N
% Pro:
0
0
10
0
10
0
0
0
0
0
0
10
0
19
10
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
19
0
0
0
19
46
10
0
% R
% Ser:
10
46
46
0
46
19
0
55
10
10
10
0
0
10
10
% S
% Thr:
46
10
10
0
0
10
19
0
0
0
0
0
10
0
0
% T
% Val:
0
10
0
19
19
0
10
0
0
0
0
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
46
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _