KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGFBRAP1
All Species:
24.85
Human Site:
S777
Identified Species:
68.33
UniProt:
Q8WUH2
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUH2
NP_001136093.1
860
97158
S777
L
M
G
A
M
R
D
S
I
H
A
R
R
T
M
Chimpanzee
Pan troglodytes
XP_525844
989
111193
S906
L
M
G
A
M
R
D
S
I
H
A
R
R
T
V
Rhesus Macaque
Macaca mulatta
XP_001108695
860
97284
S777
L
M
G
A
M
R
D
S
V
H
A
K
R
T
M
Dog
Lupus familis
XP_538441
937
105315
S854
L
T
G
A
V
R
N
S
V
H
A
R
R
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3UR70
860
97285
S777
L
M
G
A
M
R
D
S
I
H
A
R
R
T
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517348
630
72238
M553
E
N
I
H
T
Q
R
M
T
Q
V
A
A
G
L
Chicken
Gallus gallus
XP_416922
863
98244
S776
L
A
G
A
V
R
Q
S
I
H
T
K
R
M
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IG72
863
97029
T778
L
C
G
A
M
R
A
T
V
H
A
R
C
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184902
469
52851
Y392
D
T
A
L
L
K
L
Y
A
E
S
N
P
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.3
97.6
81.9
N.A.
89.3
N.A.
N.A.
59.7
78.5
N.A.
63
N.A.
N.A.
N.A.
N.A.
27.5
Protein Similarity:
100
86.7
98.8
86.5
N.A.
95.1
N.A.
N.A.
67
90.1
N.A.
79.4
N.A.
N.A.
N.A.
N.A.
38.1
P-Site Identity:
100
93.3
86.6
66.6
N.A.
93.3
N.A.
N.A.
0
53.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
N.A.
N.A.
13.3
66.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
78
0
0
12
0
12
0
67
12
12
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
12
0
0
0
0
0
45
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
78
0
0
0
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
12
0
0
0
0
0
78
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
45
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
0
0
0
0
23
0
0
12
% K
% Leu:
78
0
0
12
12
0
12
0
0
0
0
0
0
0
12
% L
% Met:
0
45
0
0
56
0
0
12
0
0
0
0
0
12
23
% M
% Asn:
0
12
0
0
0
0
12
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
0
0
0
0
0
12
12
0
0
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
78
12
0
0
0
0
56
67
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
0
12
0
0
0
12
% S
% Thr:
0
23
0
0
12
0
0
12
12
0
12
0
0
78
34
% T
% Val:
0
0
0
0
23
0
0
0
34
0
12
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _