KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGFBRAP1
All Species:
26.97
Human Site:
Y608
Identified Species:
74.17
UniProt:
Q8WUH2
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUH2
NP_001136093.1
860
97158
Y608
K
R
L
Q
K
E
E
Y
H
T
H
L
A
V
L
Chimpanzee
Pan troglodytes
XP_525844
989
111193
Y737
K
R
L
Q
K
E
E
Y
H
T
H
L
A
V
L
Rhesus Macaque
Macaca mulatta
XP_001108695
860
97284
Y608
K
R
L
Q
K
E
E
Y
H
T
H
L
A
V
L
Dog
Lupus familis
XP_538441
937
105315
Y685
R
R
L
Q
K
E
E
Y
H
T
H
L
A
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UR70
860
97285
Y608
R
R
L
Q
K
E
E
Y
H
T
H
L
A
I
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517348
630
72238
V404
A
N
G
N
S
V
E
V
S
E
M
Q
V
K
L
Chicken
Gallus gallus
XP_416922
863
98244
Y607
R
K
I
E
K
E
K
Y
H
T
H
L
A
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IG72
863
97029
Y608
K
K
L
Q
K
E
K
Y
H
T
H
L
A
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184902
469
52851
L243
S
N
K
E
V
Y
A
L
V
P
L
P
V
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.3
97.6
81.9
N.A.
89.3
N.A.
N.A.
59.7
78.5
N.A.
63
N.A.
N.A.
N.A.
N.A.
27.5
Protein Similarity:
100
86.7
98.8
86.5
N.A.
95.1
N.A.
N.A.
67
90.1
N.A.
79.4
N.A.
N.A.
N.A.
N.A.
38.1
P-Site Identity:
100
100
100
86.6
N.A.
86.6
N.A.
N.A.
13.3
60
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
13.3
93.3
N.A.
100
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
12
0
0
0
0
0
78
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
23
0
78
67
0
0
12
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
78
0
78
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
45
23
12
0
78
0
23
0
0
0
0
0
0
12
12
% K
% Leu:
0
0
67
0
0
0
0
12
0
0
12
78
0
12
89
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
23
0
12
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% P
% Gln:
0
0
0
67
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
34
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
78
0
0
0
0
0
% T
% Val:
0
0
0
0
12
12
0
12
12
0
0
0
23
45
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _