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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC7
All Species:
14.85
Human Site:
S198
Identified Species:
36.3
UniProt:
Q8WUI4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUI4
NP_001091886.1
952
102927
S198
A
E
T
L
G
D
S
S
P
S
S
S
S
T
P
Chimpanzee
Pan troglodytes
XP_522368
1190
127415
S436
A
E
T
L
G
D
S
S
P
S
S
S
S
T
P
Rhesus Macaque
Macaca mulatta
XP_001110599
496
53137
Dog
Lupus familis
XP_543715
962
103756
S197
A
E
T
L
G
D
S
S
P
S
S
S
S
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C2B3
938
101268
S221
A
E
T
L
G
D
S
S
P
S
S
S
S
T
P
Rat
Rattus norvegicus
Q99P99
1077
118634
D288
K
R
P
L
D
V
T
D
S
A
C
S
S
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510939
1082
119892
D292
K
R
P
L
D
V
T
D
S
A
C
N
S
A
P
Chicken
Gallus gallus
P83038
1080
119449
D288
K
R
P
L
D
V
T
D
S
A
C
N
S
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034447
1023
113222
S258
R
S
L
D
M
A
E
S
A
C
S
S
A
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17323
816
88964
G147
S
N
S
V
T
A
N
G
N
G
H
D
N
G
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
47.2
92.6
N.A.
86.1
47.4
N.A.
45.9
46.9
N.A.
46.4
N.A.
N.A.
N.A.
31.9
N.A.
Protein Similarity:
100
79.6
48.5
95
N.A.
89.3
59.6
N.A.
58.9
58.5
N.A.
60.9
N.A.
N.A.
N.A.
47.7
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
26.6
N.A.
20
20
N.A.
20
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
40
N.A.
40
40
N.A.
26.6
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
0
20
0
0
10
30
0
0
10
30
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
30
0
0
0
0
% C
% Asp:
0
0
0
10
30
40
0
30
0
0
0
10
0
0
0
% D
% Glu:
0
40
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
40
0
0
10
0
10
0
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
70
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
0
10
0
0
20
10
0
0
% N
% Pro:
0
0
30
0
0
0
0
0
40
0
0
0
0
10
70
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
30
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
10
10
10
0
0
0
40
50
30
40
50
60
70
0
0
% S
% Thr:
0
0
40
0
10
0
30
0
0
0
0
0
0
40
0
% T
% Val:
0
0
0
10
0
30
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _