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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC7
All Species:
29.7
Human Site:
S582
Identified Species:
72.59
UniProt:
Q8WUI4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUI4
NP_001091886.1
952
102927
S582
E
E
L
Q
S
V
H
S
E
R
H
V
L
L
Y
Chimpanzee
Pan troglodytes
XP_522368
1190
127415
S820
E
E
L
Q
S
V
H
S
E
R
H
V
L
L
Y
Rhesus Macaque
Macaca mulatta
XP_001110599
496
53137
P170
Q
R
M
F
V
M
L
P
C
G
G
V
G
V
D
Dog
Lupus familis
XP_543715
962
103756
S592
E
E
L
Q
S
V
H
S
E
R
H
V
L
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8C2B3
938
101268
S569
E
E
L
Q
S
V
H
S
E
R
H
V
L
L
Y
Rat
Rattus norvegicus
Q99P99
1077
118634
S714
E
E
L
Q
T
V
H
S
E
A
H
T
L
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510939
1082
119892
S719
E
E
L
Q
T
V
H
S
E
A
H
T
L
L
Y
Chicken
Gallus gallus
P83038
1080
119449
S712
E
E
L
Q
T
V
H
S
E
A
H
T
L
L
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034447
1023
113222
S661
E
E
L
Q
T
V
H
S
E
A
H
V
L
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17323
816
88964
N491
A
C
L
K
I
D
A
N
S
L
P
L
K
R
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
47.2
92.6
N.A.
86.1
47.4
N.A.
45.9
46.9
N.A.
46.4
N.A.
N.A.
N.A.
31.9
N.A.
Protein Similarity:
100
79.6
48.5
95
N.A.
89.3
59.6
N.A.
58.9
58.5
N.A.
60.9
N.A.
N.A.
N.A.
47.7
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
80
N.A.
80
80
N.A.
86.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
100
86.6
N.A.
86.6
86.6
N.A.
93.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
40
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% D
% Glu:
80
80
0
0
0
0
0
0
80
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
80
0
0
0
80
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
90
0
0
0
10
0
0
10
0
10
80
80
0
% L
% Met:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% P
% Gln:
10
0
0
80
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
40
0
0
0
10
0
% R
% Ser:
0
0
0
0
40
0
0
80
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
40
0
0
0
0
0
0
30
0
0
0
% T
% Val:
0
0
0
0
10
80
0
0
0
0
0
60
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _