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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STYX All Species: 17.58
Human Site: S184 Identified Species: 42.96
UniProt: Q8WUJ0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUJ0 NP_001124173.1 223 25492 S184 K L T I Q M M S P L Q I E R S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082157 223 25503 S184 K L T I Q M M S P L Q I E R S
Dog Lupus familis XP_547814 195 22069 P157 L T I Q M M S P L Q I E R S L
Cat Felis silvestris
Mouse Mus musculus Q60969 223 25412 S184 K L T I Q M M S P L Q I E R S
Rat Rattus norvegicus Q64623 367 39523 G322 P H C S A E A G S P A M A V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515512 244 28052 T205 K L T I Q M M T P L Q L E R S
Chicken Gallus gallus
Frog Xenopus laevis Q4V7N3 223 25232 S184 K L T I K M M S P L Q L G R P
Zebra Danio Brachydanio rerio Q566R7 183 20613 Q145 F Q T G E L Q Q F R E W L K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394795 229 26038 Q191 R E Y E P I Y Q A Q K T L K S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786563 146 16534 F107 C I S V N D G F A S Q L K E Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.2 83.8 N.A. 96.4 21.5 N.A. 77.8 N.A. 84.3 27.7 N.A. N.A. 51.5 N.A. 41.2
Protein Similarity: 100 N.A. 99 86 N.A. 99 37 N.A. 84 N.A. 91 43.9 N.A. N.A. 66.8 N.A. 52.9
P-Site Identity: 100 N.A. 100 6.6 N.A. 100 0 N.A. 86.6 N.A. 73.3 6.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 6.6 N.A. 100 6.6 N.A. 100 N.A. 86.6 33.3 N.A. N.A. 33.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 10 0 20 0 10 0 10 0 0 % A
% Cys: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 10 10 10 0 0 0 0 10 10 40 10 10 % E
% Phe: 10 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 10 10 0 0 0 0 10 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 50 0 10 0 0 0 0 10 30 0 0 0 % I
% Lys: 50 0 0 0 10 0 0 0 0 0 10 0 10 20 0 % K
% Leu: 10 50 0 0 0 10 0 0 10 50 0 30 20 0 20 % L
% Met: 0 0 0 0 10 60 50 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 10 0 0 10 50 10 0 0 0 0 10 % P
% Gln: 0 10 0 10 40 0 10 20 0 20 60 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 10 0 0 10 50 0 % R
% Ser: 0 0 10 10 0 0 10 40 10 10 0 0 0 10 50 % S
% Thr: 0 10 60 0 0 0 0 10 0 0 0 10 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _