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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STYX All Species: 20.3
Human Site: Y134 Identified Species: 49.63
UniProt: Q8WUJ0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUJ0 NP_001124173.1 223 25492 Y134 S A A F V I A Y I M E T F G M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082157 223 25503 Y134 S A A F V I A Y I M E T F G M
Dog Lupus familis XP_547814 195 22069 M113 Y I M E T F G M K Y R D A F A
Cat Felis silvestris
Mouse Mus musculus Q60969 223 25412 Y134 S A A F V I A Y I M E T F G M
Rat Rattus norvegicus Q64623 367 39523 Y272 S A T I C L A Y L M R T N R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515512 244 28052 Y155 S A A L V I A Y I M E T F G V
Chicken Gallus gallus
Frog Xenopus laevis Q4V7N3 223 25232 Y134 S A A L V I A Y I M E T F G I
Zebra Danio Brachydanio rerio Q566R7 183 20613 A101 R S V T L V V A Y I M T V T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394795 229 26038 A144 N A G I S R S A A L V L A Y V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786563 146 16534 H63 S G G R I L V H G N A G I S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.2 83.8 N.A. 96.4 21.5 N.A. 77.8 N.A. 84.3 27.7 N.A. N.A. 51.5 N.A. 41.2
Protein Similarity: 100 N.A. 99 86 N.A. 99 37 N.A. 84 N.A. 91 43.9 N.A. N.A. 66.8 N.A. 52.9
P-Site Identity: 100 N.A. 100 0 N.A. 100 40 N.A. 86.6 N.A. 86.6 6.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 0 N.A. 100 60 N.A. 93.3 N.A. 93.3 33.3 N.A. N.A. 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 70 50 0 0 0 60 20 10 0 10 0 20 0 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 50 0 0 0 0 % E
% Phe: 0 0 0 30 0 10 0 0 0 0 0 0 50 10 0 % F
% Gly: 0 10 20 0 0 0 10 0 10 0 0 10 0 50 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 20 10 50 0 0 50 10 0 0 10 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 20 10 20 0 0 10 10 0 10 0 0 0 % L
% Met: 0 0 10 0 0 0 0 10 0 60 10 0 0 0 30 % M
% Asn: 10 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 10 0 10 0 0 0 0 20 0 0 10 10 % R
% Ser: 70 10 0 0 10 0 10 0 0 0 0 0 0 10 0 % S
% Thr: 0 0 10 10 10 0 0 0 0 0 0 70 0 10 10 % T
% Val: 0 0 10 0 50 10 20 0 0 0 10 0 10 0 30 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 60 10 10 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _