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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STYX All Species: 20
Human Site: Y23 Identified Species: 48.89
UniProt: Q8WUJ0 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUJ0 NP_001124173.1 223 25492 Y23 E D A E E W T Y P M R R E M Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082157 223 25503 Y23 E D A E E W T Y P M R R E M Q
Dog Lupus familis XP_547814 195 22069 K20 Y S S A M K S K L P I L Q K Y
Cat Felis silvestris
Mouse Mus musculus Q60969 223 25412 Y23 D D A E E W T Y P M R R E M Q
Rat Rattus norvegicus Q64623 367 39523 F119 E A R S T Q V F F L Q G G Y E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515512 244 28052 Y44 A G N R D W T Y P M R R E M Q
Chicken Gallus gallus
Frog Xenopus laevis Q4V7N3 223 25232 Y23 E E A E D W A Y P M R R E M Q
Zebra Danio Brachydanio rerio Q566R7 183 20613 V8 M G N G I N K V L P D L Y L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394795 229 26038 Y39 D G P K E W T Y T M R R H M Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786563 146 16534
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.2 83.8 N.A. 96.4 21.5 N.A. 77.8 N.A. 84.3 27.7 N.A. N.A. 51.5 N.A. 41.2
Protein Similarity: 100 N.A. 99 86 N.A. 99 37 N.A. 84 N.A. 91 43.9 N.A. N.A. 66.8 N.A. 52.9
P-Site Identity: 100 N.A. 100 0 N.A. 93.3 6.6 N.A. 66.6 N.A. 80 0 N.A. N.A. 60 N.A. 0
P-Site Similarity: 100 N.A. 100 20 N.A. 100 33.3 N.A. 73.3 N.A. 93.3 6.6 N.A. N.A. 73.3 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 40 10 0 0 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 30 0 0 20 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 40 10 0 40 40 0 0 0 0 0 0 0 50 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % F
% Gly: 0 30 0 10 0 0 0 0 0 0 0 10 10 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 10 0 10 10 10 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 20 10 0 20 0 10 0 % L
% Met: 10 0 0 0 10 0 0 0 0 60 0 0 0 60 0 % M
% Asn: 0 0 20 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 50 20 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 10 0 10 0 60 % Q
% Arg: 0 0 10 10 0 0 0 0 0 0 60 60 0 0 0 % R
% Ser: 0 10 10 10 0 0 10 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 10 0 50 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 60 0 0 0 0 10 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _