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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYB5D2
All Species:
17.88
Human Site:
S181
Identified Species:
30.26
UniProt:
Q8WUJ1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUJ1
NP_653212.1
264
28690
S181
P
C
N
A
E
W
S
S
A
R
G
S
R
L
W
Chimpanzee
Pan troglodytes
XP_511279
208
22411
C133
A
R
G
S
R
L
W
C
S
Q
K
S
G
G
V
Rhesus Macaque
Macaca mulatta
XP_001093128
264
28902
S181
P
C
N
A
E
W
S
S
A
R
G
S
R
L
W
Dog
Lupus familis
XP_546555
263
28295
S180
P
C
N
A
E
W
S
S
G
R
G
S
R
L
W
Cat
Felis silvestris
Mouse
Mus musculus
Q5SSH8
263
29144
S181
P
C
N
S
E
W
S
S
A
K
G
S
R
L
W
Rat
Rattus norvegicus
Q6AY62
263
29046
S181
P
C
N
A
E
W
S
S
A
K
G
S
R
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516188
183
19692
G109
A
E
A
A
I
A
E
G
L
R
A
R
A
R
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CES0
267
29696
R152
P
V
G
K
L
I
G
R
F
Y
T
E
T
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W376
287
32609
E209
G
C
N
I
E
W
S
E
E
R
G
T
R
V
W
Honey Bee
Apis mellifera
XP_001120049
206
23597
K132
P
P
C
N
I
E
W
K
P
D
S
G
T
V
V
Nematode Worm
Caenorhab. elegans
Q9XXA7
326
36224
Q244
P
C
N
S
E
Y
N
Q
N
G
G
R
V
W
C
Sea Urchin
Strong. purpuratus
XP_795139
281
30858
N158
E
D
W
V
K
F
F
N
N
E
Y
T
Y
V
G
Poplar Tree
Populus trichocarpa
XP_002323190
250
27832
D148
K
L
V
G
R
Y
Y
D
S
E
G
N
P
T
K
Maize
Zea mays
NP_001136676
237
26324
G153
V
E
V
K
A
K
R
G
T
Q
L
L
E
K
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.4
95.8
79.9
N.A.
80.6
80.3
N.A.
41.2
N.A.
N.A.
44.9
N.A.
35.8
34.4
35.5
38.7
Protein Similarity:
100
74.6
97.7
85.2
N.A.
88.6
88.6
N.A.
50
N.A.
N.A.
60.6
N.A.
49.1
52.6
48.7
54.8
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
93.3
N.A.
13.3
N.A.
N.A.
6.6
N.A.
60
6.6
33.3
0
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
100
N.A.
13.3
N.A.
N.A.
6.6
N.A.
73.3
13.3
53.3
33.3
Percent
Protein Identity:
32.5
35.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
49.6
52.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
36
8
8
0
0
29
0
8
0
8
0
0
% A
% Cys:
0
50
8
0
0
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
8
% D
% Glu:
8
15
0
0
50
8
8
8
8
15
0
8
8
0
0
% E
% Phe:
0
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
15
8
0
0
8
15
8
8
58
8
8
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
15
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
15
8
8
0
8
0
15
8
0
0
8
8
% K
% Leu:
0
8
0
0
8
8
0
0
8
0
8
8
0
36
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
50
8
0
0
8
8
15
0
0
8
0
0
0
% N
% Pro:
58
8
0
0
0
0
0
0
8
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
15
0
0
0
0
15
% Q
% Arg:
0
8
0
0
15
0
8
8
0
36
0
15
43
8
0
% R
% Ser:
0
0
0
22
0
0
43
36
15
0
8
43
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
8
15
15
8
0
% T
% Val:
8
8
15
8
0
0
0
0
0
0
0
0
8
22
15
% V
% Trp:
0
0
8
0
0
43
15
0
0
0
0
0
0
8
43
% W
% Tyr:
0
0
0
0
0
15
8
0
0
8
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _