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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5D2 All Species: 0.91
Human Site: T134 Identified Species: 1.54
UniProt: Q8WUJ1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUJ1 NP_653212.1 264 28690 T134 Y V C V G R V T G R F Y G E D
Chimpanzee Pan troglodytes XP_511279 208 22411 G86 G R F Y G E D G L P T P A L T
Rhesus Macaque Macaca mulatta XP_001093128 264 28902 I134 Y V C V G R V I G R F Y G E D
Dog Lupus familis XP_546555 263 28295 I133 Y E L V G R V I G R F Y G E D
Cat Felis silvestris
Mouse Mus musculus Q5SSH8 263 29144 V134 Y V F V G R L V G R F Y R K D
Rat Rattus norvegicus Q6AY62 263 29046 I134 Y V F V G R L I G R F Y G K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516188 183 19692 A62 D V S D L S P A Q M L T L H N
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CES0 267 29696 R105 F T G K D A S R A F I T G D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W376 287 32609 I162 Y V Y K G R V I G R F Y D E K
Honey Bee Apis mellifera XP_001120049 206 23597 A85 L S I Q Q V K A L N D W V Q F
Nematode Worm Caenorhab. elegans Q9XXA7 326 36224 A197 Y P L V G V V A D L Y Y D S E
Sea Urchin Strong. purpuratus XP_795139 281 30858 G111 T K H Y G P G G G Y S F F A G
Poplar Tree Populus trichocarpa XP_002323190 250 27832 V101 R D A S R A F V S G N F T G D
Maize Zea mays NP_001136676 237 26324 S106 S L Q G L S S S E V N S V V D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.4 95.8 79.9 N.A. 80.6 80.3 N.A. 41.2 N.A. N.A. 44.9 N.A. 35.8 34.4 35.5 38.7
Protein Similarity: 100 74.6 97.7 85.2 N.A. 88.6 88.6 N.A. 50 N.A. N.A. 60.6 N.A. 49.1 52.6 48.7 54.8
P-Site Identity: 100 6.6 93.3 80 N.A. 66.6 73.3 N.A. 6.6 N.A. N.A. 6.6 N.A. 66.6 0 33.3 13.3
P-Site Similarity: 100 6.6 93.3 80 N.A. 80 86.6 N.A. 13.3 N.A. N.A. 20 N.A. 66.6 13.3 46.6 20
Percent
Protein Identity: 32.5 35.9 N.A. N.A. N.A. N.A.
Protein Similarity: 49.6 52.2 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 15 0 22 8 0 0 0 8 8 0 % A
% Cys: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 8 8 0 8 0 8 0 8 0 15 8 50 % D
% Glu: 0 8 0 0 0 8 0 0 8 0 0 0 0 29 8 % E
% Phe: 8 0 22 0 0 0 8 0 0 8 43 15 8 0 15 % F
% Gly: 8 0 8 8 65 0 8 15 50 8 0 0 36 8 8 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 8 0 0 0 0 29 0 0 8 0 0 0 0 % I
% Lys: 0 8 0 15 0 0 8 0 0 0 0 0 0 15 8 % K
% Leu: 8 8 15 0 15 0 15 0 15 8 8 0 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 15 0 0 0 8 % N
% Pro: 0 8 0 0 0 8 8 0 0 8 0 8 0 0 0 % P
% Gln: 0 0 8 8 8 0 0 0 8 0 0 0 0 8 0 % Q
% Arg: 8 8 0 0 8 43 0 8 0 43 0 0 8 0 0 % R
% Ser: 8 8 8 8 0 15 15 8 8 0 8 8 0 8 0 % S
% Thr: 8 8 0 0 0 0 0 8 0 0 8 15 8 0 8 % T
% Val: 0 43 0 43 0 15 36 15 0 8 0 0 15 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 50 0 8 15 0 0 0 0 0 8 8 50 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _