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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYB5D2 All Species: 21.82
Human Site: T145 Identified Species: 36.92
UniProt: Q8WUJ1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUJ1 NP_653212.1 264 28690 T145 Y G E D G L P T P A L T Q V E
Chimpanzee Pan troglodytes XP_511279 208 22411 A97 P A L T Q V E A A I T R G L E
Rhesus Macaque Macaca mulatta XP_001093128 264 28902 T145 Y G E D G L P T P A L T Q V E
Dog Lupus familis XP_546555 263 28295 T144 Y G E D G L P T P T L T R V E
Cat Felis silvestris
Mouse Mus musculus Q5SSH8 263 29144 T145 Y R K D G L P T S E L T Q V E
Rat Rattus norvegicus Q6AY62 263 29046 T145 Y G K D G L P T S E L T Q V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516188 183 19692 F73 T L H N W L L F Y E K N Y E F
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CES0 267 29696 G116 T G D F T E A G L S N D V S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W376 287 32609 T173 Y D E K G A L T T Y H H K F L
Honey Bee Apis mellifera XP_001120049 206 23597 N96 W V Q F Y N K N Y I Y K G K L
Nematode Worm Caenorhab. elegans Q9XXA7 326 36224 T208 Y D S E G Q P T P E L T D V L
Sea Urchin Strong. purpuratus XP_795139 281 30858 S122 F F A G R D G S K A Y I S G D
Poplar Tree Populus trichocarpa XP_002323190 250 27832 D112 F T G D G L T D S L R G L S S
Maize Zea mays NP_001136676 237 26324 F117 S V V D W R K F Y F E R Y I F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.4 95.8 79.9 N.A. 80.6 80.3 N.A. 41.2 N.A. N.A. 44.9 N.A. 35.8 34.4 35.5 38.7
Protein Similarity: 100 74.6 97.7 85.2 N.A. 88.6 88.6 N.A. 50 N.A. N.A. 60.6 N.A. 49.1 52.6 48.7 54.8
P-Site Identity: 100 6.6 100 86.6 N.A. 73.3 80 N.A. 6.6 N.A. N.A. 6.6 N.A. 26.6 0 53.3 6.6
P-Site Similarity: 100 20 100 93.3 N.A. 80 86.6 N.A. 13.3 N.A. N.A. 26.6 N.A. 33.3 13.3 60 26.6
Percent
Protein Identity: 32.5 35.9 N.A. N.A. N.A. N.A.
Protein Similarity: 49.6 52.2 N.A. N.A. N.A. N.A.
P-Site Identity: 20 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 13.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 8 8 8 8 22 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 8 50 0 8 0 8 0 0 0 8 8 0 15 % D
% Glu: 0 0 29 8 0 8 8 0 0 29 8 0 0 8 43 % E
% Phe: 15 8 0 15 0 0 0 15 0 8 0 0 0 8 15 % F
% Gly: 0 36 8 8 58 0 8 8 0 0 0 8 15 8 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 8 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 15 0 8 0 8 0 % I
% Lys: 0 0 15 8 0 0 15 0 8 0 8 8 8 8 0 % K
% Leu: 0 8 8 0 0 50 15 0 8 8 43 0 8 8 22 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 0 8 0 0 8 8 0 0 0 % N
% Pro: 8 0 0 0 0 0 43 0 29 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 8 8 0 0 0 0 0 0 29 0 0 % Q
% Arg: 0 8 0 0 8 8 0 0 0 0 8 15 8 0 0 % R
% Ser: 8 0 8 0 0 0 0 8 22 8 0 0 8 15 8 % S
% Thr: 15 8 0 8 8 0 8 50 8 8 8 43 0 0 0 % T
% Val: 0 15 8 0 0 8 0 0 0 0 0 0 8 43 0 % V
% Trp: 8 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 50 0 0 0 8 0 0 0 22 8 15 0 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _