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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYB5D2
All Species:
17.88
Human Site:
T222
Identified Species:
30.26
UniProt:
Q8WUJ1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUJ1
NP_653212.1
264
28690
T222
P
R
C
V
C
V
R
T
T
G
P
P
S
G
Q
Chimpanzee
Pan troglodytes
XP_511279
208
22411
M174
T
G
P
P
S
G
Q
M
P
D
S
P
P
H
R
Rhesus Macaque
Macaca mulatta
XP_001093128
264
28902
T222
P
R
C
V
C
V
R
T
T
G
P
P
S
D
Q
Dog
Lupus familis
XP_546555
263
28295
T221
P
H
C
V
C
V
R
T
T
G
P
P
S
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q5SSH8
263
29144
T222
P
H
C
V
C
V
R
T
T
G
P
P
S
D
Q
Rat
Rattus norvegicus
Q6AY62
263
29046
T222
P
H
C
V
C
V
R
T
T
G
P
P
S
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516188
183
19692
P150
Q
R
R
R
D
A
G
P
P
G
R
P
G
Q
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CES0
267
29696
S193
Q
L
Y
P
S
C
N
S
E
W
S
E
A
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W376
287
32609
P250
S
F
Q
C
A
C
V
P
D
A
E
L
D
E
I
Honey Bee
Apis mellifera
XP_001120049
206
23597
V173
K
E
Y
R
C
A
C
V
K
L
D
S
K
E
Y
Nematode Worm
Caenorhab. elegans
Q9XXA7
326
36224
F285
R
C
A
C
V
K
N
F
G
P
G
V
S
G
A
Sea Urchin
Strong. purpuratus
XP_795139
281
30858
D199
G
R
R
L
K
A
N
D
A
E
H
K
K
Q
Y
Poplar Tree
Populus trichocarpa
XP_002323190
250
27832
S189
P
S
C
N
S
R
W
S
Q
G
E
G
G
E
V
Maize
Zea mays
NP_001136676
237
26324
R194
G
Y
P
R
L
V
R
R
P
G
D
I
A
L
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.4
95.8
79.9
N.A.
80.6
80.3
N.A.
41.2
N.A.
N.A.
44.9
N.A.
35.8
34.4
35.5
38.7
Protein Similarity:
100
74.6
97.7
85.2
N.A.
88.6
88.6
N.A.
50
N.A.
N.A.
60.6
N.A.
49.1
52.6
48.7
54.8
P-Site Identity:
100
6.6
93.3
86.6
N.A.
86.6
86.6
N.A.
20
N.A.
N.A.
0
N.A.
0
6.6
13.3
6.6
P-Site Similarity:
100
20
93.3
86.6
N.A.
86.6
86.6
N.A.
20
N.A.
N.A.
13.3
N.A.
0
6.6
13.3
13.3
Percent
Protein Identity:
32.5
35.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
49.6
52.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
22
0
0
8
8
0
0
15
0
15
% A
% Cys:
0
8
43
15
43
15
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
8
8
15
0
8
29
0
% D
% Glu:
0
8
0
0
0
0
0
0
8
8
15
8
0
22
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
15
8
0
0
0
8
8
0
8
58
8
8
15
15
8
% G
% His:
0
22
0
0
0
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
8
0
0
0
8
8
0
0
8
0
0
8
15
0
0
% K
% Leu:
0
8
0
8
8
0
0
0
0
8
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
22
0
0
0
0
0
0
0
0
% N
% Pro:
43
0
15
15
0
0
0
15
22
8
36
50
8
0
0
% P
% Gln:
15
0
8
0
0
0
8
0
8
0
0
0
0
15
36
% Q
% Arg:
8
29
15
22
0
8
43
8
0
0
8
0
0
0
8
% R
% Ser:
8
8
0
0
22
0
0
15
0
0
15
8
43
8
0
% S
% Thr:
8
0
0
0
0
0
0
36
36
0
0
0
0
0
8
% T
% Val:
0
0
0
36
8
43
8
8
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% W
% Tyr:
0
8
15
0
0
0
0
0
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _