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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPMT1
All Species:
20
Human Site:
S139
Identified Species:
40
UniProt:
Q8WUK0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUK0
NP_001137456.1
201
22844
S139
C
K
A
G
R
S
R
S
A
T
M
V
A
A
Y
Chimpanzee
Pan troglodytes
P0C594
220
25358
S154
C
V
M
G
R
S
R
S
A
T
L
V
L
A
Y
Rhesus Macaque
Macaca mulatta
XP_001105550
201
22737
S139
C
K
A
G
R
S
R
S
A
T
M
V
A
A
Y
Dog
Lupus familis
XP_540742
275
29812
S213
C
K
A
G
R
S
R
S
A
T
M
V
A
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q66GT5
193
21924
R136
Y
V
H
C
K
A
G
R
S
R
S
A
T
M
V
Rat
Rattus norvegicus
P0C089
193
21868
R136
Y
V
H
C
K
A
G
R
S
R
S
A
T
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513242
119
13331
M62
G
R
S
R
S
A
T
M
V
A
A
Y
L
I
E
Chicken
Gallus gallus
P0C597
214
24304
S146
C
A
M
G
R
S
R
S
A
T
L
V
L
A
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
S146
C
V
M
G
R
S
R
S
A
T
L
V
L
A
Y
Fruit Fly
Dros. melanogaster
Q86BN8
200
23137
A143
S
V
Y
V
H
C
K
A
G
R
T
R
S
A
T
Honey Bee
Apis mellifera
XP_393660
192
22665
A135
S
V
Y
V
H
C
K
A
G
R
T
R
S
A
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200325
192
22497
L135
A
T
L
V
G
C
Y
L
M
M
M
N
H
C
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.7
96.5
64.7
N.A.
81
81
N.A.
37.8
20.5
N.A.
N.A.
24.7
42.2
40.2
N.A.
42.2
Protein Similarity:
100
38.1
98
69
N.A.
89.5
89
N.A.
49.7
35.5
N.A.
N.A.
38.1
62.6
59.2
N.A.
61.6
P-Site Identity:
100
73.3
100
100
N.A.
0
0
N.A.
0
73.3
N.A.
N.A.
73.3
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
80
100
100
N.A.
20
20
N.A.
20
80
N.A.
N.A.
80
26.6
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
25
0
0
25
0
17
50
9
9
17
25
67
0
% A
% Cys:
50
0
0
17
0
25
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
50
9
0
17
0
17
0
0
0
0
0
0
% G
% His:
0
0
17
0
17
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
25
0
0
17
0
17
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
0
0
9
0
0
25
0
34
0
0
% L
% Met:
0
0
25
0
0
0
0
9
9
9
34
0
0
17
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
9
50
0
50
17
0
34
0
17
0
0
0
% R
% Ser:
17
0
9
0
9
50
0
50
17
0
17
0
17
0
0
% S
% Thr:
0
9
0
0
0
0
9
0
0
50
17
0
17
0
25
% T
% Val:
0
50
0
25
0
0
0
0
9
0
0
50
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
17
0
0
0
9
0
0
0
0
9
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _