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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPMT1
All Species:
8.79
Human Site:
Y129
Identified Species:
17.58
UniProt:
Q8WUK0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUK0
NP_001137456.1
201
22844
Y129
Q
S
L
G
Q
C
V
Y
V
H
C
K
A
G
R
Chimpanzee
Pan troglodytes
P0C594
220
25358
L144
R
D
D
H
S
K
I
L
V
H
C
V
M
G
R
Rhesus Macaque
Macaca mulatta
XP_001105550
201
22737
Y129
Q
S
L
G
Q
C
V
Y
V
H
C
K
A
G
R
Dog
Lupus familis
XP_540742
275
29812
Y203
Q
S
L
G
Q
S
V
Y
V
H
C
K
A
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q66GT5
193
21924
Q126
L
K
Y
Q
A
L
G
Q
C
V
Y
V
H
C
K
Rat
Rattus norvegicus
P0C089
193
21868
Q126
L
K
Y
Q
S
L
G
Q
C
V
Y
V
H
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513242
119
13331
C52
G
N
S
V
Y
V
H
C
K
A
G
R
S
R
S
Chicken
Gallus gallus
P0C597
214
24304
L136
Q
D
E
R
N
K
V
L
V
H
C
A
M
G
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
L136
L
S
Q
P
H
N
V
L
V
H
C
V
M
G
R
Fruit Fly
Dros. melanogaster
Q86BN8
200
23137
N133
S
S
S
Y
Q
P
E
N
V
G
S
V
Y
V
H
Honey Bee
Apis mellifera
XP_393660
192
22665
H125
I
N
S
D
K
S
Y
H
P
K
S
V
Y
V
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200325
192
22497
T125
V
H
C
K
A
G
R
T
R
S
A
T
L
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.7
96.5
64.7
N.A.
81
81
N.A.
37.8
20.5
N.A.
N.A.
24.7
42.2
40.2
N.A.
42.2
Protein Similarity:
100
38.1
98
69
N.A.
89.5
89
N.A.
49.7
35.5
N.A.
N.A.
38.1
62.6
59.2
N.A.
61.6
P-Site Identity:
100
33.3
100
93.3
N.A.
0
0
N.A.
0
46.6
N.A.
N.A.
46.6
20
0
N.A.
0
P-Site Similarity:
100
46.6
100
93.3
N.A.
6.6
6.6
N.A.
20
46.6
N.A.
N.A.
46.6
20
20
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
0
9
9
9
25
0
0
% A
% Cys:
0
0
9
0
0
17
0
9
17
0
50
0
0
17
0
% C
% Asp:
0
17
9
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
25
0
9
17
0
0
9
9
0
0
50
9
% G
% His:
0
9
0
9
9
0
9
9
0
50
0
0
17
0
17
% H
% Ile:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
9
9
17
0
0
9
9
0
25
0
0
17
% K
% Leu:
25
0
25
0
0
17
0
25
0
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% M
% Asn:
0
17
0
0
9
9
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
9
0
0
9
0
0
0
0
0
0
% P
% Gln:
34
0
9
17
34
0
0
17
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
9
0
0
9
0
9
0
0
9
0
9
50
% R
% Ser:
9
42
25
0
17
17
0
0
0
9
17
0
9
0
9
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% T
% Val:
9
0
0
9
0
9
42
0
59
17
0
50
0
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
9
9
0
9
25
0
0
17
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _