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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP133 All Species: 13.33
Human Site: S253 Identified Species: 36.67
UniProt: Q8WUM0 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUM0 NP_060700.2 1156 128979 S253 P Q G Q G M L S G I G R K V S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536351 1156 129196 S253 P Q G Q G M L S G I G R K V S
Cat Felis silvestris
Mouse Mus musculus Q8R0G9 1155 128669 S252 P Q G Q G M L S G I G R R V S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521408 1141 125602 I243 G Q G V L S G I G R R V S S L
Chicken Gallus gallus XP_419576 1181 131489 S281 P Q G Q G M F S G I G R K V S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998696 1136 126547 F242 G R R V S S L F G I R G Q P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651080 1200 135128 G264 K P A T S F L G G F G K K F A
Honey Bee Apis mellifera XP_395203 1123 127402 K244 V T E T K L V K V T C T T L G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781849 1215 136348 Q254 Q L D G L F K Q Q F Q R E M G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 91 N.A. 83 N.A. N.A. 70.5 71.6 N.A. 58.2 N.A. 27.3 32.5 N.A. 29.8
Protein Similarity: 100 N.A. N.A. 95.7 N.A. 92.3 N.A. N.A. 83.3 83.5 N.A. 76.1 N.A. 48.9 52.5 N.A. 47.5
P-Site Identity: 100 N.A. N.A. 100 N.A. 93.3 N.A. N.A. 20 93.3 N.A. 20 N.A. 26.6 0 N.A. 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 N.A. N.A. 20 93.3 N.A. 40 N.A. 40 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 23 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % C
% Asp: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 12 0 0 0 0 0 0 0 0 0 12 0 0 % E
% Phe: 0 0 0 0 0 23 12 12 0 23 0 0 0 12 0 % F
% Gly: 23 0 56 12 45 0 12 12 78 0 56 12 0 0 23 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 12 0 56 0 0 0 0 0 % I
% Lys: 12 0 0 0 12 0 12 12 0 0 0 12 45 0 0 % K
% Leu: 0 12 0 0 23 12 56 0 0 0 0 0 0 12 12 % L
% Met: 0 0 0 0 0 45 0 0 0 0 0 0 0 12 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 45 12 0 0 0 0 0 0 0 0 0 0 0 12 0 % P
% Gln: 12 56 0 45 0 0 0 12 12 0 12 0 12 0 0 % Q
% Arg: 0 12 12 0 0 0 0 0 0 12 23 56 12 0 0 % R
% Ser: 0 0 0 0 23 23 0 45 0 0 0 0 12 12 45 % S
% Thr: 0 12 0 23 0 0 0 0 0 12 0 12 12 0 0 % T
% Val: 12 0 0 23 0 0 12 0 12 0 0 12 0 45 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _