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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP133
All Species:
9.39
Human Site:
S499
Identified Species:
25.83
UniProt:
Q8WUM0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUM0
NP_060700.2
1156
128979
S499
S
S
V
A
G
P
N
S
E
S
M
I
F
E
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536351
1156
129196
N499
S
S
V
A
G
P
S
N
E
S
M
V
F
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0G9
1155
128669
S498
S
S
V
G
G
R
G
S
E
S
M
V
F
E
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521408
1141
125602
P487
S
S
V
A
G
P
H
P
E
P
S
L
L
D
S
Chicken
Gallus gallus
XP_419576
1181
131489
S527
S
S
V
A
G
P
I
S
E
S
P
A
F
D
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998696
1136
126547
K489
T
P
L
E
T
P
P
K
I
D
M
V
A
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651080
1200
135128
S517
P
D
L
Y
A
P
N
S
C
N
A
S
F
A
V
Honey Bee
Apis mellifera
XP_395203
1123
127402
Y487
E
E
V
Q
D
M
F
Y
S
S
D
N
C
T
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781849
1215
136348
L539
V
A
K
L
S
R
E
L
I
D
D
F
P
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
91
N.A.
83
N.A.
N.A.
70.5
71.6
N.A.
58.2
N.A.
27.3
32.5
N.A.
29.8
Protein Similarity:
100
N.A.
N.A.
95.7
N.A.
92.3
N.A.
N.A.
83.3
83.5
N.A.
76.1
N.A.
48.9
52.5
N.A.
47.5
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
73.3
N.A.
N.A.
46.6
66.6
N.A.
13.3
N.A.
26.6
13.3
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
80
N.A.
N.A.
73.3
73.3
N.A.
40
N.A.
40
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
45
12
0
0
0
0
0
12
12
12
23
12
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% C
% Asp:
0
12
0
0
12
0
0
0
0
23
23
0
0
23
0
% D
% Glu:
12
12
0
12
0
0
12
0
56
0
0
0
0
34
12
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
12
56
0
0
% F
% Gly:
0
0
0
12
56
0
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
23
0
0
12
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
23
12
0
0
0
12
0
0
0
12
12
0
0
% L
% Met:
0
0
0
0
0
12
0
0
0
0
45
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
23
12
0
12
0
12
0
0
0
% N
% Pro:
12
12
0
0
0
67
12
12
0
12
12
0
12
0
12
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
12
12
% Q
% Arg:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% R
% Ser:
56
56
0
0
12
0
12
45
12
56
12
12
0
0
23
% S
% Thr:
12
0
0
0
12
0
0
0
0
0
0
0
0
12
23
% T
% Val:
12
0
67
0
0
0
0
0
0
0
0
34
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _