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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP133
All Species:
10.3
Human Site:
S549
Identified Species:
28.33
UniProt:
Q8WUM0
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUM0
NP_060700.2
1156
128979
S549
D
E
L
F
S
S
H
S
D
L
D
S
D
S
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536351
1156
129196
S549
D
E
L
F
S
S
H
S
D
M
D
S
D
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0G9
1155
128669
T548
D
E
L
F
S
S
H
T
D
L
D
S
D
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521408
1141
125602
P535
M
V
D
E
L
F
S
P
E
A
D
S
E
T
E
Chicken
Gallus gallus
XP_419576
1181
131489
A577
V
E
L
F
P
S
N
A
D
V
D
S
D
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998696
1136
126547
D536
G
E
G
S
A
D
L
D
T
V
V
T
Q
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651080
1200
135128
D595
D
P
S
G
A
P
M
D
A
Y
K
L
D
R
I
Honey Bee
Apis mellifera
XP_395203
1123
127402
T534
D
I
D
A
N
L
D
T
L
I
L
K
V
A
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781849
1215
136348
N608
D
L
P
Q
T
T
H
N
L
L
S
E
H
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
91
N.A.
83
N.A.
N.A.
70.5
71.6
N.A.
58.2
N.A.
27.3
32.5
N.A.
29.8
Protein Similarity:
100
N.A.
N.A.
95.7
N.A.
92.3
N.A.
N.A.
83.3
83.5
N.A.
76.1
N.A.
48.9
52.5
N.A.
47.5
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
86.6
N.A.
N.A.
20
60
N.A.
6.6
N.A.
13.3
6.6
N.A.
26.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
93.3
N.A.
N.A.
40
86.6
N.A.
33.3
N.A.
20
40
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
23
0
0
12
12
12
0
0
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
67
0
23
0
0
12
12
23
45
0
56
0
56
0
12
% D
% Glu:
0
56
0
12
0
0
0
0
12
0
0
12
12
0
67
% E
% Phe:
0
0
0
45
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
12
12
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
45
0
0
0
0
0
12
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
12
0
0
0
12
12
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
12
% K
% Leu:
0
12
45
0
12
12
12
0
23
34
12
12
0
0
0
% L
% Met:
12
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
12
12
0
0
0
0
0
0
0
% N
% Pro:
0
12
12
0
12
12
0
12
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% R
% Ser:
0
0
12
12
34
45
12
23
0
0
12
56
0
12
0
% S
% Thr:
0
0
0
0
12
12
0
23
12
0
0
12
0
12
0
% T
% Val:
12
12
0
0
0
0
0
0
0
23
12
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _