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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP133 All Species: 33.33
Human Site: Y1057 Identified Species: 91.67
UniProt: Q8WUM0 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUM0 NP_060700.2 1156 128979 Y1057 K A L D L L E Y I D E E E D I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536351 1156 129196 Y1057 K A L D L L E Y I D E E E D V
Cat Felis silvestris
Mouse Mus musculus Q8R0G9 1155 128669 Y1056 K A L D L L E Y I D E E E D V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521408 1141 125602 Y1042 K A L D L L E Y I N E E E D V
Chicken Gallus gallus XP_419576 1181 131489 Y1082 K A L D L L E Y I D E E E E V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998696 1136 126547 Y1034 K A L D L L E Y F E E E N G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651080 1200 135128 Y1100 K A L E L L S Y V E Q P Y D M
Honey Bee Apis mellifera XP_395203 1123 127402 Y1029 K A L D L L K Y M E Q E D E K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781849 1215 136348 Y1115 K A L D L L Q Y L H K E G S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 91 N.A. 83 N.A. N.A. 70.5 71.6 N.A. 58.2 N.A. 27.3 32.5 N.A. 29.8
Protein Similarity: 100 N.A. N.A. 95.7 N.A. 92.3 N.A. N.A. 83.3 83.5 N.A. 76.1 N.A. 48.9 52.5 N.A. 47.5
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 93.3 N.A. N.A. 86.6 86.6 N.A. 73.3 N.A. 46.6 53.3 N.A. 53.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 N.A. N.A. 100 100 N.A. 80 N.A. 80 93.3 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 89 0 0 0 0 0 45 0 0 12 56 0 % D
% Glu: 0 0 0 12 0 0 67 0 0 34 67 89 56 23 0 % E
% Phe: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 12 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 56 0 0 0 0 0 23 % I
% Lys: 100 0 0 0 0 0 12 0 0 0 12 0 0 0 12 % K
% Leu: 0 0 100 0 100 100 0 0 12 0 0 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 12 % M
% Asn: 0 0 0 0 0 0 0 0 0 12 0 0 12 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % P
% Gln: 0 0 0 0 0 0 12 0 0 0 23 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 12 0 0 0 0 0 0 12 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 45 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _