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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD6IP
All Species:
34.24
Human Site:
S421
Identified Species:
53.81
UniProt:
Q8WUM4
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUM4
NP_037506.2
868
96023
S421
P
Q
S
I
L
T
K
S
R
S
V
I
E
Q
G
Chimpanzee
Pan troglodytes
XP_001169526
868
96035
S421
P
Q
S
I
L
T
K
S
R
S
V
I
E
Q
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534215
869
96105
S421
P
Q
S
I
L
T
K
S
T
S
V
I
E
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU78
869
95992
S421
P
Q
S
I
L
T
K
S
T
S
V
V
E
Q
G
Rat
Rattus norvegicus
Q9QZA2
873
96612
S426
P
Q
S
I
L
T
K
S
T
A
V
V
E
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520983
801
88429
E374
Q
L
I
K
E
L
P
E
L
L
Q
R
N
R
E
Chicken
Gallus gallus
NP_001026164
882
97297
S425
P
Q
S
I
L
N
K
S
K
A
V
I
E
Q
G
Frog
Xenopus laevis
Q9W6C5
867
96180
S420
P
Q
S
I
L
N
K
S
K
T
V
I
E
Q
G
Zebra Danio
Brachydanio rerio
NP_998525
866
95753
S418
P
Q
S
I
L
E
K
S
R
A
L
I
Q
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651582
836
92520
L398
T
Q
T
L
N
A
V
L
A
S
L
N
L
P
A
Honey Bee
Apis mellifera
XP_396117
816
91664
I387
K
L
R
E
M
T
Q
I
L
N
G
V
L
A
S
Nematode Worm
Caenorhab. elegans
P34552
882
98246
K427
L
P
E
S
L
K
L
K
S
A
K
L
K
Q
N
Sea Urchin
Strong. purpuratus
XP_001204017
886
97596
S423
P
Q
S
V
L
E
K
S
Q
G
I
K
Q
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12033
661
75929
Y234
H
L
K
A
K
K
A
Y
F
S
A
V
T
Y
Y
Red Bread Mold
Neurospora crassa
Q7SAN9
1012
112176
D436
Q
D
I
L
P
D
E
D
F
R
T
W
C
V
D
Conservation
Percent
Protein Identity:
100
99.8
N.A.
97
N.A.
94.2
94.1
N.A.
81.6
83.9
76.9
73.1
N.A.
42.2
43
39.2
46.3
Protein Similarity:
100
99.8
N.A.
97.9
N.A.
96.6
96.3
N.A.
85.7
90.6
88.8
85
N.A.
60.9
60.9
57.2
63.8
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
0
80
80
73.3
N.A.
13.3
6.6
13.3
46.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
6.6
93.3
93.3
93.3
N.A.
33.3
33.3
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
29.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
44
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
7
0
7
27
7
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
7
0
0
0
7
0
7
0
0
0
0
0
0
7
% D
% Glu:
0
0
7
7
7
14
7
7
0
0
0
0
47
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
60
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
14
54
0
0
0
7
0
0
7
40
0
0
0
% I
% Lys:
7
0
7
7
7
14
60
7
14
0
7
7
7
7
0
% K
% Leu:
7
20
0
14
67
7
7
7
14
7
14
7
14
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
14
0
0
0
7
0
7
7
0
7
% N
% Pro:
60
7
0
0
7
0
7
0
0
0
0
0
0
7
0
% P
% Gln:
14
67
0
0
0
0
7
0
7
0
7
0
14
60
0
% Q
% Arg:
0
0
7
0
0
0
0
0
20
7
0
7
0
7
0
% R
% Ser:
0
0
60
7
0
0
0
60
7
40
0
0
0
0
7
% S
% Thr:
7
0
7
0
0
40
0
0
20
7
7
0
7
0
0
% T
% Val:
0
0
0
7
0
0
7
0
0
0
47
27
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _