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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDCD6IP All Species: 34.24
Human Site: S421 Identified Species: 53.81
UniProt: Q8WUM4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUM4 NP_037506.2 868 96023 S421 P Q S I L T K S R S V I E Q G
Chimpanzee Pan troglodytes XP_001169526 868 96035 S421 P Q S I L T K S R S V I E Q G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534215 869 96105 S421 P Q S I L T K S T S V I E Q G
Cat Felis silvestris
Mouse Mus musculus Q9WU78 869 95992 S421 P Q S I L T K S T S V V E Q G
Rat Rattus norvegicus Q9QZA2 873 96612 S426 P Q S I L T K S T A V V E Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520983 801 88429 E374 Q L I K E L P E L L Q R N R E
Chicken Gallus gallus NP_001026164 882 97297 S425 P Q S I L N K S K A V I E Q G
Frog Xenopus laevis Q9W6C5 867 96180 S420 P Q S I L N K S K T V I E Q G
Zebra Danio Brachydanio rerio NP_998525 866 95753 S418 P Q S I L E K S R A L I Q Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651582 836 92520 L398 T Q T L N A V L A S L N L P A
Honey Bee Apis mellifera XP_396117 816 91664 I387 K L R E M T Q I L N G V L A S
Nematode Worm Caenorhab. elegans P34552 882 98246 K427 L P E S L K L K S A K L K Q N
Sea Urchin Strong. purpuratus XP_001204017 886 97596 S423 P Q S V L E K S Q G I K Q K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12033 661 75929 Y234 H L K A K K A Y F S A V T Y Y
Red Bread Mold Neurospora crassa Q7SAN9 1012 112176 D436 Q D I L P D E D F R T W C V D
Conservation
Percent
Protein Identity: 100 99.8 N.A. 97 N.A. 94.2 94.1 N.A. 81.6 83.9 76.9 73.1 N.A. 42.2 43 39.2 46.3
Protein Similarity: 100 99.8 N.A. 97.9 N.A. 96.6 96.3 N.A. 85.7 90.6 88.8 85 N.A. 60.9 60.9 57.2 63.8
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 80 N.A. 0 80 80 73.3 N.A. 13.3 6.6 13.3 46.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 6.6 93.3 93.3 93.3 N.A. 33.3 33.3 33.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.1 29.5
Protein Similarity: N.A. N.A. N.A. N.A. 40.3 44
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 7 7 0 7 27 7 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 7 0 0 0 7 0 7 0 0 0 0 0 0 7 % D
% Glu: 0 0 7 7 7 14 7 7 0 0 0 0 47 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 60 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 14 54 0 0 0 7 0 0 7 40 0 0 0 % I
% Lys: 7 0 7 7 7 14 60 7 14 0 7 7 7 7 0 % K
% Leu: 7 20 0 14 67 7 7 7 14 7 14 7 14 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 14 0 0 0 7 0 7 7 0 7 % N
% Pro: 60 7 0 0 7 0 7 0 0 0 0 0 0 7 0 % P
% Gln: 14 67 0 0 0 0 7 0 7 0 7 0 14 60 0 % Q
% Arg: 0 0 7 0 0 0 0 0 20 7 0 7 0 7 0 % R
% Ser: 0 0 60 7 0 0 0 60 7 40 0 0 0 0 7 % S
% Thr: 7 0 7 0 0 40 0 0 20 7 7 0 7 0 0 % T
% Val: 0 0 0 7 0 0 7 0 0 0 47 27 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _